BACKGROUND: Persistent drug-resistant psychotic symptoms are a pervasive problem in the treatment of schizophrenia. AIMS: To evaluate the durability of the treatment effects of cognitive-behavioural therapy for chronic schizophrenia one year after treatment termination. METHOD: A comparison of clinical outcomes was made at one-year follow-up from a randomised trial of cognitive-behavioural therapy, supportive counselling and routine care alone in the treatment of chronic schizophrenia. RESULTS:Seventy out of the 72 patients (97%) who completed treatment were assessed at follow-up. There were significant differences between the three groups when positive and negative symptoms were analysed by means of ANCOVAs. Between-group comparisons indicated significant differences between cognitive-behavioural therapy and routine care at follow-up for positive symptoms. There was a trend towards significance for both cognitive-behavioural therapy and supportive counselling to be superior to routine care alone on negative symptoms. CONCLUSIONS: At 12-month follow-up the significant advantage of cognitive-behavioural therapy compared to routine care alone remained.
RCT Entities:
BACKGROUND: Persistent drug-resistant psychotic symptoms are a pervasive problem in the treatment of schizophrenia. AIMS: To evaluate the durability of the treatment effects of cognitive-behavioural therapy for chronic schizophrenia one year after treatment termination. METHOD: A comparison of clinical outcomes was made at one-year follow-up from a randomised trial of cognitive-behavioural therapy, supportive counselling and routine care alone in the treatment of chronic schizophrenia. RESULTS: Seventy out of the 72 patients (97%) who completed treatment were assessed at follow-up. There were significant differences between the three groups when positive and negative symptoms were analysed by means of ANCOVAs. Between-group comparisons indicated significant differences between cognitive-behavioural therapy and routine care at follow-up for positive symptoms. There was a trend towards significance for both cognitive-behavioural therapy and supportive counselling to be superior to routine care alone on negative symptoms. CONCLUSIONS: At 12-month follow-up the significant advantage of cognitive-behavioural therapy compared to routine care alone remained.
Authors: Stefan Klingberg; Wolfgang Wölwer; Corinna Engel; Andreas Wittorf; Jutta Herrlich; Christoph Meisner; Gerhard Buchkremer; Georg Wiedemann Journal: Schizophr Bull Date: 2011-09 Impact factor: 9.306
Authors: Moogeh Baharnoori; Cali Bartholomeusz; Aurelie A Boucher; Lisa Buchy; Christopher Chaddock; Bonga Chiliza; Melanie Föcking; Alex Fornito; Juan A Gallego; Hiroaki Hori; Gisele Huf; Gul A Jabbar; Shi Hyun Kang; Yousri El Kissi; Jessica Merchán-Naranjo; Gemma Modinos; Nashaat A M Abdel-Fadeel; Anna-Karin Neubeck; Hsiao Piau Ng; Gabriela Novak; Olasunmbo O Owolabi; Diana P Prata; Naren P Rao; Igor Riecansky; Darryl C Smith; Renan P Souza; Renate Thienel; Hanan D Trotman; Hiroyuki Uchida; Kristen A Woodberry; Anne O'Shea; Lynn E DeLisi Journal: Schizophr Res Date: 2010-10-08 Impact factor: 4.939
Authors: Christopher Jones; David Hacker; Jun Xia; Alan Meaden; Claire B Irving; Sai Zhao; Jue Chen; Chunhu Shi Journal: Cochrane Database Syst Rev Date: 2018-12-20
Authors: Christopher Jones; David Hacker; Alan Meaden; Irene Cormac; Claire B Irving; Jun Xia; Sai Zhao; Chunhu Shi; Jue Chen Journal: Cochrane Database Syst Rev Date: 2018-11-15