Literature DB >> 10615894

Abeta42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease.

A Mochizuki, A Tamaoka, A Shimohata, Y Komatsuzaki, S Shoji.   

Abstract

Immunohistochemistry with end-specific antibodies against C-termini of Abeta40 and Abeta42 in Alzheimer's disease showed that Abeta42 immunoreactivity was localised intracellularly in subpopulations of neurons of patients with Alzheimer's disease.

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Year:  2000        PMID： 10615894     DOI： 10.1016/S0140-6736(99)04937-5

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  26 in total

1.  Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.

Authors:  L Gasparini; G K Gouras; R Wang; R S Gross; M F Beal; P Greengard; H Xu
Journal:  J Neurosci       Date:  2001-04-15       Impact factor: 6.167

Review 2.  From Alzheimer to Huntington: why is a structural understanding so difficult?

Authors:  Piero Andrea Temussi; Laura Masino; Annalisa Pastore
Journal:  EMBO J       Date:  2003-02-03       Impact factor: 11.598

3.  Association of ApoE and LRP mRNA levels with dementia and AD neuropathology.

Authors:  Afia Akram; James Schmeidler; Pavel Katsel; Patrick R Hof; Vahram Haroutunian
Journal:  Neurobiol Aging       Date:  2011-06-15       Impact factor: 4.673

4.  Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology.

Authors:  Reisuke H Takahashi; Teresa A Milner; Feng Li; Ellen E Nam; Mark A Edgar; Haruyasu Yamaguchi; M Flint Beal; Huaxi Xu; Paul Greengard; Gunnar K Gouras
Journal:  Am J Pathol       Date:  2002-11       Impact factor: 4.307

5.  Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain.

Authors:  M Morishima-Kawashima; N Oshima; H Ogata; H Yamaguchi; M Yoshimura; S Sugihara; Y Ihara
Journal:  Am J Pathol       Date:  2000-12       Impact factor: 4.307

Review 6.  Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease.

Authors:  Gunnar K Gouras; Davide Tampellini; Reisuke H Takahashi; Estibaliz Capetillo-Zarate
Journal:  Acta Neuropathol       Date:  2010-03-31       Impact factor: 17.088

7.  Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease.

Authors:  Thomas A Bayer; Oliver Wirths
Journal:  Front Aging Neurosci       Date:  2010-03-10       Impact factor: 5.750

8.  Endocytic pathways mediating oligomeric Abeta42 neurotoxicity.

Authors:  Chunjiang Yu; Evelyn Nwabuisi-Heath; Kevin Laxton; Mary Jo Ladu
Journal:  Mol Neurodegener       Date:  2010-05-17       Impact factor: 14.195

9.  Accumulation of intraneuronal Abeta correlates with ApoE4 genotype.

Authors:  Ditte Z Christensen; Thomas Schneider-Axmann; Paul J Lucassen; Thomas A Bayer; Oliver Wirths
Journal:  Acta Neuropathol       Date:  2010-03-10       Impact factor: 17.088

10.  HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons.

Authors:  Joseph F Poduslo; Emily J Gilles; Muthu Ramakrishnan; Kyle G Howell; Thomas M Wengenack; Geoffry L Curran; Karunya K Kandimalla
Journal:  PLoS One       Date:  2010-01-21       Impact factor: 3.240
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