Literature DB >> 10614989

Localization of B2 bradykinin receptor mRNA in the rat retina and sclerocornea.

H Takeda1, Y Kimura, H Higashida, S Yokoyama.   

Abstract

The expression of the B2 bradykinin receptor (BKR) mRNA in the adult rat eye was investigated by RNA blot and in situ hybridization analyses. Blot hybridization analysis of poly(A)+ RNA from the whole eye identified RNA species of 6000 and 4000 nucleotides, consistent with those observed in brain, lung, kidney and uterus. In situ hybridization analysis using digoxigenin-labeled riboprobes revealed intense labeling in the retinal ganglion cell layer and in a population of cells adjacent to the sclerocorneal junction. These data suggest that the B2 BKR is involved in biological processes in both retina and sclerocornea.

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Year:  1999        PMID: 10614989     DOI: 10.1016/s0162-3109(99)00057-0

Source DB:  PubMed          Journal:  Immunopharmacology        ISSN: 0162-3109


  9 in total

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