Literature DB >> 10614672

Loss of atheroprotective effect of estradiol in immunodeficient mice.

R Elhage1, S Clamens, C Reardon-Alulis, G S Getz, C Fievet, A Maret, J F Arnal, F Bayard.   

Abstract

Estradiol significantly decreases fatty streak formation in the aortic root of chow-fed apolipoprotein E-deficient mice. In contrast, immunodeficient mice with homozygous disruption at the recombinase activating gene 2 loci present fatty streak development that is insensitive to estradiol. Lymphocytes thus appear to be required for development of the atheroprotective effect of estradiol in this mouse model.

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Year:  2000        PMID： 10614672     DOI： 10.1210/endo.141.1.7377

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  6 in total

1.  Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice.

Authors:  S C Whitman; P Ravisankar; H Elam; A Daugherty
Journal:  Am J Pathol       Date:  2000-12       Impact factor: 4.307

2.  Total lymphocyte deficiency attenuates AngII-induced atherosclerosis in males but not abdominal aortic aneurysms in apoE deficient mice.

Authors:  Haruhito A Uchida; Fjoralba Kristo; Debra L Rateri; Hong Lu; Richard Charnigo; Lisa A Cassis; Alan Daugherty
Journal:  Atherosclerosis       Date:  2010-03-04       Impact factor: 5.162

3.  The atheroprotective effect of 17beta-estradiol depends on complex interactions in adaptive immunity.

Authors:  Rima Elhage; Pierre Gourdy; Jacek Jawien; Laurent Brouchet; Caroine Castano; Catherine Fievet; Göran K Hansson; Jean-François Arnal; Francis Bayard
Journal:  Am J Pathol       Date:  2005-07       Impact factor: 4.307

4.  Deleting TCR alpha beta+ or CD4+ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice.

Authors:  Rima Elhage; Pierre Gourdy; Laurent Brouchet; Jacek Jawien; Marie-José Fouque; Catherine Fiévet; Xavier Huc; Yara Barreira; Jean Claude Couloumiers; Jean-François Arnal; Francis Bayard
Journal:  Am J Pathol       Date:  2004-12       Impact factor: 4.307

Review 5.  Estrogen Receptor and Vascular Aging.

Authors:  Morgane Davezac; Melissa Buscato; Rana Zahreddine; Patrick Lacolley; Daniel Henrion; Francoise Lenfant; Jean-Francois Arnal; Coralie Fontaine
Journal:  Front Aging       Date:  2021-09-24

Review 6.  The Impact of Estrogen Receptor in Arterial and Lymphatic Vascular Diseases.

Authors:  Coralie Fontaine; Florent Morfoisse; Florence Tatin; Audrey Zamora; Rana Zahreddine; Daniel Henrion; Jean-François Arnal; Françoise Lenfant; Barbara Garmy-Susini
Journal:  Int J Mol Sci       Date:  2020-05-04       Impact factor: 5.923
  6 in total

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