| Literature DB >> 10612836 |
G Isidro1, I Veiga, P Matos, S Almeida, S Bizarro, B Marshall, M Baptista, J Leite, F Regateiro, J Soares, S Castedo, M G Boavida.
Abstract
Hereditary non-polyposis colorectal cancer (HNPCC) is considered to be determined by germline mutations in the mismatch repair (MMR) genes, especially MSH2 and MLH1. While screening for mutations in these two genes in HNPCC portuguese families, 3 previously unreported MSH2 and 1 MLH1 mutations have been identified in families meeting strict Amsterdam criteria. Hum Mutat 15:116, 2000. Copyright 2000 Wiley-Liss, Inc.Entities:
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Year: 2000 PMID： 10612836 DOI： 10.1002/(SICI)1098-1004(200001)15:1<116::AID-HUMU24>3.0.CO;2-Q
Source DB: PubMed Journal: Hum Mutat ISSN： 1059-7794 Impact factor: 4.878