Literature DB >> 10612576

Pulmonary capillaritis associated with the antiphospholipid antibody syndrome and rapid response to plasmapheresis.

G W Waterer1, B Latham, J A Waring, E Gabbay.   

Abstract

OBJECTIVE: Pulmonary capillaritis is an uncommon complication of antiphospholipid antibody syndrome but has important therapeutic implications. CASE REPORT: A patient with antiphospholipid antibody syndrome presented with haemoptysis and respiratory failure. Investigation including open lung biopsy, demonstrated vasculitis as the underlying pathology, rather than thrombosis. The patient responded promptly to methylprednisolone, cyclophosphamide and plasmapheresis.
CONCLUSION: Plasmapheresis has not previously been described in this setting and the rapid response suggests that it should be considered in severe disease.

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Year:  1999        PMID: 10612576     DOI: 10.1046/j.1440-1843.1999.00212.x

Source DB:  PubMed          Journal:  Respirology        ISSN: 1323-7799            Impact factor:   6.424


  3 in total

Review 1.  The lung in the antiphospholipid syndrome.

Authors:  G Espinosa; R Cervera; J Font; R A Asherson
Journal:  Ann Rheum Dis       Date:  2002-03       Impact factor: 19.103

Review 2.  Update on diffuse alveolar hemorrhage and pulmonary vasculitis.

Authors:  Megan L Krause; Rodrigo Cartin-Ceba; Ulrich Specks; Tobias Peikert
Journal:  Immunol Allergy Clin North Am       Date:  2012-09-28       Impact factor: 3.479

Review 3.  Clinical Insights into Diffuse Alveolar Hemorrhage in Antiphospholipid Syndrome.

Authors:  Sarah Abramson Stoots; Lindsay Lief; Doruk Erkan
Journal:  Curr Rheumatol Rep       Date:  2019-09-06       Impact factor: 4.592

  3 in total

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