Literature DB >> 10612303

A three-dimensional analysis of flow in the pivot regions of an ATS bileaflet valve.

S G Kelly1, P R Verdonck, J A Vierendeels, K Riemslagh, E Dick, G G Van Nooten.   

Abstract

Bileaflet heart valves are currently the most commonly implanted type of mechanical prosthetic valve, because of their low transvalvular pressure drop, centralised flow and durability. However, in common with all mechanical heart valves, implanted bileaflet valves show an inherent tendency for blood clot formation at the valve site. Fluid dynamical phenomena associated with blood clotting are elevated blood shear stresses and regions of persistent blood recirculation, particularly when both occur together. Using three-dimensional CFD modelling, combined with enlarged scale experimental modelling, we investigated the blood flow through the ATS bileaflet valve during forward flow, with particular attention to the leaflet pivot regions. Recirculating regions were found both within and downstream of the valve housing ring. Qualitative assessment of the entire cardiac cycle suggested that recirculating blood within the housing ring will be washed away whilst the valve is closed, but as with all bileaflet valve designs recirculating blood downstream of the valve may have a residence time much longer than one cardiac cycle.

Mesh:

Year:  1999        PMID: 10612303

Source DB:  PubMed          Journal:  Int J Artif Organs        ISSN: 0391-3988            Impact factor:   1.595


  5 in total

1.  Device Thrombogenicity Emulator (DTE)--design optimization methodology for cardiovascular devices: a study in two bileaflet MHV designs.

Authors:  Michalis Xenos; Gaurav Girdhar; Yared Alemu; Jolyon Jesty; Marvin Slepian; Shmuel Einav; Danny Bluestein
Journal:  J Biomech       Date:  2010-05-21       Impact factor: 2.712

2.  Numerical investigation of the performance of three hinge designs of bileaflet mechanical heart valves.

Authors:  Hélène A Simon; Liang Ge; Fotis Sotiropoulos; Ajit P Yoganathan
Journal:  Ann Biomed Eng       Date:  2010-06-23       Impact factor: 3.934

Review 3.  Towards non-thrombogenic performance of blood recirculating devices.

Authors:  D Bluestein; K B Chandran; K B Manning
Journal:  Ann Biomed Eng       Date:  2010-02-04       Impact factor: 3.934

4.  Device thrombogenicity emulation: a novel methodology for optimizing the thromboresistance of cardiovascular devices.

Authors:  Danny Bluestein; Gaurav Girdhar; Shmuel Einav; Marvin J Slepian
Journal:  J Biomech       Date:  2012-12-06       Impact factor: 2.712

5.  Simulation of the three-dimensional hinge flow fields of a bileaflet mechanical heart valve under aortic conditions.

Authors:  Hélène A Simon; Liang Ge; Iman Borazjani; Fotis Sotiropoulos; Ajit P Yoganathan
Journal:  Ann Biomed Eng       Date:  2009-12-04       Impact factor: 3.934

  5 in total

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