Literature DB >> 10609755

Characterization of genetic defects of hemophilia A in mainland China.

Y Z Zhang1, J X Liu, H Z Shao, Z W Chi, H L Wang, S J Chen, Z Chen, Z Y Wang, W Huang.   

Abstract

Southern blotting, PCR, DGGE and DNA sequencing were used to study gene mutations in 52 unrelated Chinese Hemophilia A patients. 18 out of 34 severe cases had intron 22 inversions, 13 had small gene lesions, of which five are novel.

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Year:  1999        PMID: 10609755     DOI: 10.1016/s1050-3862(99)00005-4

Source DB:  PubMed          Journal:  Genet Anal


  2 in total

1.  Identification of novel mutations in exon 14 of the f8 gene in malaysian patients with severe hemophilia a.

Authors:  Emmanuel Jairaj Moses; Sim Pei Ling; Faisal Muti Al-Hassan; Faraizah Abdul Karim; Narazah Mohd Yusoff
Journal:  Indian J Clin Biochem       Date:  2011-09-30

2.  Severe Hemophilia A in a Male Old English Sheep Dog with a C→T Transition that Created a Premature Stop Codon in Factor VIII.

Authors:  Jay N Lozier; Mark T Kloos; Elizabeth P Merricks; Nathaly Lemoine; Margaret H Whitford; Robin A Raymer; Dwight A Bellinger; Timothy C Nichols
Journal:  Comp Med       Date:  2016       Impact factor: 0.982

  2 in total

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