Literature DB >> 10607584

B-cell commitment: Pax5 is the deciding factor.

T Enver1.   

Abstract

Recent studies have identified the transcription factor Pax5 as a critical determinant of commitment to the B-lymphocyte pathway. Surprisingly, Pax5 appears to achieve this primarily through suppressing alternative haematopoietic lineage fates.

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Year:  1999        PMID： 10607584     DOI： 10.1016/s0960-9822(00)80108-6

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

1.  Modeling early Epstein-Barr virus infection in Drosophila melanogaster: the BZLF1 protein.

Authors:  Amy L Adamson; Natasha Wright; Dennis R LaJeunesse
Journal:  Genetics       Date:  2005-08-03       Impact factor: 4.562

2.  Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas.

Authors:  Xia Liu; Jiaji G Chen; Manit Munshi; Zachary R Hunter; Lian Xu; Amanda Kofides; Nickolas Tsakmaklis; Maria G Demos; Maria Luisa Guerrera; Gloria G Chan; Cristina Jimenez; Christopher J Patterson; Kirsten Meid; Andrew Keezer; Jorge J Castillo; Steven P Treon; Guang Yang
Journal:  Blood Adv       Date:  2020-01-14

3.  Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1.

Authors:  Jiyeon Yu; Sumi Kim; Nari Lee; Hyoeun Jeon; Jun Lee; Masamichi Takami; Jaerang Rho
Journal:  Int J Mol Sci       Date:  2021-02-20       Impact factor: 5.923

4.  Functional definition of a transcription factor hierarchy regulating T cell lineage commitment.

Authors:  Laura Garcia-Perez; Farbod Famili; Martijn Cordes; Martijn Brugman; Marja van Eggermond; Haoyu Wu; Jihed Chouaref; David San León Granado; Machteld M Tiemessen; Karin Pike-Overzet; Lucia Daxinger; Frank J T Staal
Journal:  Sci Adv       Date:  2020-07-31       Impact factor: 14.136
  4 in total

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