Literature DB >> 10607354

The treatment of actinic keratoses.

S M Dinehart1.   

Abstract

BACKGROUND: Actinic keratoses are epidermal tumors that can develop into invasive squamous cell carcinoma. Recently, some Medicare carriers have limited reimbursement for destruction of actinic keratoses.
OBJECTIVE: We review treatments for actinic keratoses and the rationale for their use.
METHODS: Computerized literature searches were performed in MEDLINE. The search terms were "actinic keratoses" and "solar keratosis." Information from these searches was combined with considerable personal experience for the body of this work.
RESULTS: Many effective treatments for actinic keratoses exist. Cryosurgery and curettage are the most commonly used treatments. Cryosurgery is considered the standard of care for treatment of actinic keratoses. Topical 5-fluorouracil is used in 3. 6% of cases and is rarely used alone on the first patient visit. Many other effective, less commonly used treatments are available.
CONCLUSION: A physician should select the best treatment by considering features of the lesion(s) and the patient being treated. All actinic keratoses cannot be treated in the same manner. The failure to treat actinic keratoses may have serious consequences for the patient.

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Year:  2000        PMID: 10607354     DOI: 10.1067/mjd.2000.103338

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  13 in total

1.  Topical imiquimod therapy for actinic keratosis: is long-term clearance a realistic benefit?

Authors: 
Journal:  J Clin Aesthet Dermatol       Date:  2008-09

2.  Long-term Follow up of Diclofenac Sodium 3% in 2.5% Hyaluronic Acid Gel for Actinic Keratosis: One-year Evaluation.

Authors:  Christopher Nelson; Darrell Rigel
Journal:  J Clin Aesthet Dermatol       Date:  2009-07

3.  Safety and Efficacy of Multiple 16-week Courses of Topical Imiquimod for the Treatment of Large Areas of Skin Involved with Actinic Keratoses.

Authors:  James Q Del Rosso; Howard Sofen; Barry Leshin; Tc Meng; James Kulp; Sharon Levy
Journal:  J Clin Aesthet Dermatol       Date:  2009-04

Review 4.  [Cryosurgical treatment of actinic keratoses and evidence-based review].

Authors:  C C Zouboulis; H Röhrs
Journal:  Hautarzt       Date:  2005-04       Impact factor: 0.751

Review 5.  Interventions for actinic keratoses.

Authors:  Aditya K Gupta; Maryse Paquet; Elmer Villanueva; William Brintnell
Journal:  Cochrane Database Syst Rev       Date:  2012-12-12

6.  Considerations for use of Fluorouracil cream 0.5% for the treatment of actinic keratosis in elderly patients.

Authors:  William Philip Werschler
Journal:  J Clin Aesthet Dermatol       Date:  2008-07

Review 7.  [Actinic keratoses].

Authors:  P Babilas; M Landthaler; R-M Szeimies
Journal:  Hautarzt       Date:  2003-06       Impact factor: 0.751

Review 8.  Health economic evaluation of non-melanoma skin cancer and actinic keratosis.

Authors:  Mitchell K Higashi; David L Veenstra; Paul C Langley
Journal:  Pharmacoeconomics       Date:  2004       Impact factor: 4.981

Review 9.  Pharmacoeconomic considerations in treating actinic keratosis.

Authors:  Marjorie V Neidecker; Mary Lynn Davis-Ajami; Rajesh Balkrishnan; Steven R Feldman
Journal:  Pharmacoeconomics       Date:  2009       Impact factor: 4.981

10.  In-office Painless Aminolevulinic Acid Photodynamic Therapy: A Proof of Concept Study and Clinical Experience in More Than 100 Patients.

Authors:  George M Martin
Journal:  J Clin Aesthet Dermatol       Date:  2016-02
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