BACKGROUND: Hepatic resection for hepatocellular carcinoma is now considered a relatively safe procedure, owing to refined surgical techniques and management. METHODS: Three hundred different types of hepatic resection performed in one hospital were reviewed retrospectively. The operative morbidity and mortality rates and long-term survival were assessed. RESULTS: Tumours were extirpated by lobectomy or extended lobectomy in 48 patients, by segmentectomy in 53, by subsegmentectomy in 94 and by partial resection in 105. The overall hospital mortality rate was 4 per cent (13 of 300). No operative death occurred after lobectomy or extended lobectomy. Segmentectomy and subsegmentectomy were associated with high postoperative complication and hospital mortality rates. There was a significant difference in survival rate between patients with and without a cancer-free surgical margin of more than 1.0 cm. The overall 5- and 9-year survival rates were 51 and 9 per cent respectively. Rates were 56 and 24 per cent for lobectomy or extended lobectomy. CONCLUSION: For tumours of 2.1 cm or more in size lobectomy appears to carry the least risk of postoperative complications and death in hospital and best achieves a cancer-free surgical margin.
BACKGROUND: Hepatic resection for hepatocellular carcinoma is now considered a relatively safe procedure, owing to refined surgical techniques and management. METHODS: Three hundred different types of hepatic resection performed in one hospital were reviewed retrospectively. The operative morbidity and mortality rates and long-term survival were assessed. RESULTS:Tumours were extirpated by lobectomy or extended lobectomy in 48 patients, by segmentectomy in 53, by subsegmentectomy in 94 and by partial resection in 105. The overall hospital mortality rate was 4 per cent (13 of 300). No operative death occurred after lobectomy or extended lobectomy. Segmentectomy and subsegmentectomy were associated with high postoperative complication and hospital mortality rates. There was a significant difference in survival rate between patients with and without a cancer-free surgical margin of more than 1.0 cm. The overall 5- and 9-year survival rates were 51 and 9 per cent respectively. Rates were 56 and 24 per cent for lobectomy or extended lobectomy. CONCLUSION: For tumours of 2.1 cm or more in size lobectomy appears to carry the least risk of postoperative complications and death in hospital and best achieves a cancer-free surgical margin.
Authors: Sung Hoon Kim; Sae Byeol Choi; Jae Gil Lee; Seung Up Kim; Mi-Suk Park; Do Young Kim; Jin Sub Choi; Kyung Sik Kim Journal: J Gastrointest Surg Date: 2011-02-19 Impact factor: 3.452
Authors: Karim M Eltawil; Mark Kidd; Francesco Giovinazzo; Ahmed H Helmy; Ronald R Salem Journal: World J Surg Oncol Date: 2010-05-24 Impact factor: 2.754
Authors: Georgios C Sotiropoulos; Maximilian Bockhorn; George Sgourakis; Eirini I Brokalaki; Ernesto P Molmenti; Markus Neuhäuser; Arnold Radtke; Jeremias Wohlschlaeger; Hideo A Baba; Christoph E Broelsch; Hauke Lang Journal: Dig Dis Sci Date: 2008-08-19 Impact factor: 3.199
Authors: Jae Gil Lee; Chang Mu Kang; Joon Seong Park; Kyung Sik Kim; Dong Sup Yoon; Jin Sub Choi; Woo Jung Lee; Byong Ro Kim Journal: Yonsei Med J Date: 2006-02-28 Impact factor: 2.759