K Kadonosono1, N Itoh, E Nomura, S Ohno. 1. Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Japan.
Abstract
PURPOSE: Eyes with idiopathic epiretinal membranes (ERM) often have tortuous vessels and macular edema, suggesting that eyes with ERM may have a disturbance of the macular microcirculation. The authors studied perifoveal microcirculation in eyes with ERM by means of scanning laser ophthalmoscope (SLO) fluorescein angiography. METHODS: Mean capillary blood flow velocity (CFV) was measured by SLO fluorescein angiography in 19 eyes with ERM before and 6 months after vitreous surgery and in 19 healthy control eyes. RESULTS: Mean CFV was significantly reduced in the eyes with ERM compared with the healthy control eyes (2.98 +/- 0.32 mm/sec versus 3.34 +/- 0.12 mm/sec, P < 0.05), and postoperative mean CFV was significantly increased compared with preoperative mean CFV (3.14 +/- 0.32 mm/sec versus 2.98 +/- 0.32 mm/sec, P < 0.05). CONCLUSIONS: Eyes with ERM show abnormal hemodynamics in the perifoveal capillaries. Surgical treatment of eyes with ERM results in improvement of the abnormal blood flow.
PURPOSE: Eyes with idiopathic epiretinal membranes (ERM) often have tortuous vessels and macular edema, suggesting that eyes with ERM may have a disturbance of the macular microcirculation. The authors studied perifoveal microcirculation in eyes with ERM by means of scanning laser ophthalmoscope (SLO) fluorescein angiography. METHODS: Mean capillary blood flow velocity (CFV) was measured by SLO fluorescein angiography in 19 eyes with ERM before and 6 months after vitreous surgery and in 19 healthy control eyes. RESULTS: Mean CFV was significantly reduced in the eyes with ERM compared with the healthy control eyes (2.98 +/- 0.32 mm/sec versus 3.34 +/- 0.12 mm/sec, P < 0.05), and postoperative mean CFV was significantly increased compared with preoperative mean CFV (3.14 +/- 0.32 mm/sec versus 2.98 +/- 0.32 mm/sec, P < 0.05). CONCLUSIONS: Eyes with ERM show abnormal hemodynamics in the perifoveal capillaries. Surgical treatment of eyes with ERM results in improvement of the abnormal blood flow.
Authors: Lorenzo Iuliano; Giovanni Fogliato; Giuseppe Querques; Francesco Bandello; Marco Codenotti Journal: Graefes Arch Clin Exp Ophthalmol Date: 2017-03-23 Impact factor: 3.117
Authors: Ju Liu; Yong Qian; Shunnan Yang; Li Yan; Yi Wang; Meng Gao; Limei Liu; Yuanyuan Xiao; Bin Mo; Wu Liu Journal: Exp Ther Med Date: 2017-10-18 Impact factor: 2.447