Literature DB >> 10606386

Bone non-union after osteotomy in patients treated with methotrexate.

J C Gerster1, R Bossy, J Dudler.   

Abstract

We describe 2 men with seronegative rheumatoid arthritis who presented non-union of bone after osteotomy of the tibia in one case and of a metatarsal bone in the second. Both patients were still being treated with oral low doses of methotrexate (MTX). After MTX was stopped, a prompt healing of the bone occurred. These observations suggest that MTX should be stopped temporarily in cases with delayed bone healing after surgery.

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Year:  1999        PMID: 10606386

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  5 in total

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  5 in total

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