Literature DB >> 10604756

Vinylamycin, a new depsipeptide antibiotic, from Streptomyces sp.

M Igarashi1, T Shida, Y Sasaki, N Kinoshita, H Naganawa, M Hamada, T Takeuchi.   

Abstract

A new depsipeptide antibiotic, vinylamycin, was isolated from the culture broth of an actinomycete strain. The producing organism, designated MI982-63F1, was identified as a member of Streptomyces. Vinylamycin was isolated from the culture broth by extraction with EtOAc and purified by crystallization from EtOAc. The structure of vinylamycin was determined by spectroscopic analysis and degradation studies. Vinylamycin showed antimicrobial activities against Gram-positive bacteria including MRSA.

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Year:  1999        PMID: 10604756     DOI: 10.7164/antibiotics.52.873

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  10 in total

1.  Bioactive compounds from marine actinomycetes.

Authors:  Renu Solanki; Monisha Khanna; Rup Lal
Journal:  Indian J Microbiol       Date:  2009-01-08       Impact factor: 2.461

2.  Synthesis of ent-BE-43547A1 reveals a potent hypoxia-selective anticancer agent and uncovers the biosynthetic origin of the APD-CLD natural products.

Authors:  Nikolaj L Villadsen; Kristian M Jacobsen; Ulrik B Keiding; Esben T Weibel; Bjørn Christiansen; Thomas Vosegaard; Morten Bjerring; Frank Jensen; Mogens Johannsen; Thomas Tørring; Thomas B Poulsen
Journal:  Nat Chem       Date:  2016-11-21       Impact factor: 24.427

3.  Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola.

Authors:  Ratnakar N Asolkar; Kelle C Freel; Paul R Jensen; William Fenical; Tamara P Kondratyuk; Eun-Jung Park; John M Pezzuto
Journal:  J Nat Prod       Date:  2009-03-27       Impact factor: 4.050

4.  Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways.

Authors:  Jessica C Albright; Anthony W Goering; James R Doroghazi; William W Metcalf; Neil L Kelleher
Journal:  J Ind Microbiol Biotechnol       Date:  2013-11-19       Impact factor: 3.346

5.  Microtermolides A and B from termite-associated Streptomyces sp. and structural revision of vinylamycin.

Authors:  Gavin Carr; Michael Poulsen; Jonathan L Klassen; Yanpeng Hou; Thomas P Wyche; Tim S Bugni; Cameron R Currie; Jon Clardy
Journal:  Org Lett       Date:  2012-05-16       Impact factor: 6.005

6.  Draft genome sequence of Micromonospora sp. DSW705 and distribution of biosynthetic gene clusters for depsipeptides bearing 4-amino-2,4-pentadienoate in actinomycetes.

Authors:  Hisayuki Komaki; Natsuko Ichikawa; Akira Hosoyama; Moriyuki Hamada; Enjuro Harunari; Arisa Ishikawa; Yasuhiro Igarashi
Journal:  Stand Genomic Sci       Date:  2016-10-22

7.  Draft genome sequence of Streptomyces sp. MWW064 for elucidating the rakicidin biosynthetic pathway.

Authors:  Hisayuki Komaki; Arisa Ishikawa; Natsuko Ichikawa; Akira Hosoyama; Moriyuki Hamada; Enjuro Harunari; Takuya Nihira; Watanalai Panbangred; Yasuhiro Igarashi
Journal:  Stand Genomic Sci       Date:  2016-10-21

Review 8.  Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs.

Authors:  Hefa Mangzira Kemung; Loh Teng-Hern Tan; Tahir Mehmood Khan; Kok-Gan Chan; Priyia Pusparajah; Bey-Hing Goh; Learn-Han Lee
Journal:  Front Microbiol       Date:  2018-09-24       Impact factor: 5.640

Review 9.  Sampling Terrestrial Environments for Bacterial Polyketides.

Authors:  Patrick Hill; Graham W Heberlig; Christopher N Boddy
Journal:  Molecules       Date:  2017-04-29       Impact factor: 4.411

Review 10.  Recent Achievements in Total Synthesis for Integral Structural Revisions of Marine Natural Products.

Authors:  Min Woo Ha; Jonghoon Kim; Seung-Mann Paek
Journal:  Mar Drugs       Date:  2022-02-25       Impact factor: 5.118

  10 in total

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