OBJECTIVE: To determine whether a single intraoperative dose of intravenous dexamethasone has an effect on pain after tonsillectomy. DESIGN: Double-blinded randomized controlled clinical trial. SUBJECTS:Thirty-four consecutive nonpediatric patients presenting for tonsillectomy. INTERVENTION: Patients scheduled for electrocautery tonsillectomy were randomized to receive either intravenous dexamethasone or placebo during surgery. Pain was measured twice daily for 10 days by means of a visual analog scale. RESULTS: There were no statistically significant differences between the groups, but the dexamethasone group had a trend to report less pain over the first several days. The dexamethasone group received less analgesic in the recovery room, but there were no differences between the groups in the 10 days afterward. CONCLUSIONS: There is evidence that a single dose of dexamethasone reduces pain after tonsillectomy to a small degree. A single dose was not associated with adverse effects, so the risk-benefit ratio may be favorable for this practice.
RCT Entities:
OBJECTIVE: To determine whether a single intraoperative dose of intravenous dexamethasone has an effect on pain after tonsillectomy. DESIGN: Double-blinded randomized controlled clinical trial. SUBJECTS: Thirty-four consecutive nonpediatric patients presenting for tonsillectomy. INTERVENTION: Patients scheduled for electrocautery tonsillectomy were randomized to receive either intravenous dexamethasone or placebo during surgery. Pain was measured twice daily for 10 days by means of a visual analog scale. RESULTS: There were no statistically significant differences between the groups, but the dexamethasone group had a trend to report less pain over the first several days. The dexamethasone group received less analgesic in the recovery room, but there were no differences between the groups in the 10 days afterward. CONCLUSIONS: There is evidence that a single dose of dexamethasone reduces pain after tonsillectomy to a small degree. A single dose was not associated with adverse effects, so the risk-benefit ratio may be favorable for this practice.
Authors: Se Hwan Hwang; Jee Nam Song; Yeon Min Jeong; Yeon Ji Lee; Jun Myung Kang Journal: Eur Arch Otorhinolaryngol Date: 2014-12-19 Impact factor: 2.503
Authors: Serkan Sertel; Saskia Herrmann; Henry Johannes Greten; Volker Haxsen; Samir El-Bitar; Christian Heinrich Simon; Ingo Baumann; Peter Karl Plinkert Journal: Eur Arch Otorhinolaryngol Date: 2008-11-04 Impact factor: 2.503
Authors: Jennifer Plante; Alexis F Turgeon; Ryan Zarychanski; François Lauzier; Louise Vigneault; Lynne Moore; Amélie Boutin; Dean A Fergusson Journal: BMJ Date: 2012-08-28
Authors: Stephanie Weibel; Gerta Rücker; Leopold Hj Eberhart; Nathan L Pace; Hannah M Hartl; Olivia L Jordan; Debora Mayer; Manuel Riemer; Maximilian S Schaefer; Diana Raj; Insa Backhaus; Antonia Helf; Tobias Schlesinger; Peter Kienbaum; Peter Kranke Journal: Cochrane Database Syst Rev Date: 2020-10-19