| Literature DB >> 10604193 |
M Mark1, N B Ghyselinck, O Wendling, V Dupé, B Mascrez, P Kastner, P Chambon.
Abstract
To determine the functions of retinoic acid receptors RAR and RXR, we have systematically knocked-out their genes by homologous recombination in the embryonic stem cells and generated null-mutant mice. This approach has allowed us to perform a genetic dissection of the retinoic acid signalling pathway.Entities:
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Year: 1999 PMID: 10604193 DOI: 10.1017/s0029665199000798
Source DB: PubMed Journal: Proc Nutr Soc ISSN: 0029-6651 Impact factor: 6.297