Literature DB >> 10603616

The pathology of multiple sclerosis and its evolution.

H Lassmann1.   

Abstract

The pathology of multiple sclerosis (MS) was defined more than a century ago as a chronic inflammatory process which is associated with widespread primary demyelination and glial scarring. In this short review we discuss controversial issues on (i) the relationship between inflammation and demyelination, (ii) the various possible mechanisms of myelin destruction, and (iii) axonal involvement in this disease. We suggest that the disease process of MS is more complex that previously believed.

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Mesh：

Year:  1999        PMID： 10603616      PMCID： PMC1692680          DOI： 10.1098/rstb.1999.0508

Source DB:  PubMed          Journal:  Philos Trans R Soc Lond B Biol Sci        ISSN： 0962-8436            Impact factor:   6.237


  36 in total

1.  Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization.

Authors:  M N Woodroofe; M L Cuzner
Journal:  Cytokine       Date:  1993-11       Impact factor: 3.861

2.  MHC haplotype-dependent regulation of MOG-induced EAE in rats.

Authors:  R Weissert; E Wallström; M K Storch; A Stefferl; J Lorentzen; H Lassmann; C Linington; T Olsson
Journal:  J Clin Invest       Date:  1998-09-15       Impact factor: 14.808

3.  Ultrastructure of multiple sclerosis.

Authors:  M Rodriguez; B Scheithauer
Journal:  Ultrastruct Pathol       Date:  1994 Jan-Apr       Impact factor: 1.094

4.  The significance of perivascular infiltrations in multiple sclerosis.

Authors:  A Guseo; K Jellinger
Journal:  J Neurol       Date:  1975-12-02       Impact factor: 4.849

5.  Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis.

Authors:  R Washington; J Burton; R F Todd; W Newman; L Dragovic; P Dore-Duffy
Journal:  Ann Neurol       Date:  1994-01       Impact factor: 10.422

6.  Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology.

Authors:  M K Storch; A Stefferl; U Brehm; R Weissert; E Wallström; M Kerschensteiner; T Olsson; C Linington; H Lassmann
Journal:  Brain Pathol       Date:  1998-10       Impact factor: 6.508

7.  Patterns of oligodendroglia pathology in multiple sclerosis.

Authors:  K Ozawa; G Suchanek; H Breitschopf; W Brück; H Budka; K Jellinger; H Lassmann
Journal:  Brain       Date:  1994-12       Impact factor: 13.501

8.  The adhesion molecule and cytokine profile of multiple sclerosis lesions.

Authors:  B Cannella; C S Raine
Journal:  Ann Neurol       Date:  1995-04       Impact factor: 10.422

9.  Low density lipoprotein uptake by macrophages in multiple sclerosis plaques: implications for pathogenesis.

Authors:  J Newcombe; H Li; M L Cuzner
Journal:  Neuropathol Appl Neurobiol       Date:  1994-04       Impact factor: 8.090

10.  Monocyte/macrophage differentiation in early multiple sclerosis lesions.

Authors:  W Brück; P Porada; S Poser; P Rieckmann; F Hanefeld; H A Kretzschmar; H Lassmann
Journal:  Ann Neurol       Date:  1995-11       Impact factor: 10.422
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  16 in total

1.  Identification of genetic loci controlling the characteristics and severity of brain and spinal cord lesions in experimental allergic encephalomyelitis.

Authors:  R J Butterfield; E P Blankenhorn; R J Roper; J F Zachary; R W Doerge; C Teuscher
Journal:  Am J Pathol       Date:  2000-08       Impact factor: 4.307

Review 2.  Performance and Capacity Measurement of the Lower Extremities in Multiple Sclerosis -How to Approach?

Authors:  Sıla Usar İncirli; Özlem Taşkapilioğlu
Journal:  Noro Psikiyatr Ars       Date:  2018       Impact factor: 1.339

Review 3.  HIV in the CNS: pathogenic relationships to systemic HIV disease and other CNS diseases.

Authors:  D M Rausch; M R Davis
Journal:  J Neurovirol       Date:  2001-04       Impact factor: 2.643

4.  Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions.

Authors:  B Kornek; M K Storch; R Weissert; E Wallstroem; A Stefferl; T Olsson; C Linington; M Schmidbauer; H Lassmann
Journal:  Am J Pathol       Date:  2000-07       Impact factor: 4.307

5.  Changes in gait and fatigue from morning to afternoon in people with multiple sclerosis.

Authors:  M E Morris; C Cantwell; L Vowels; K Dodd
Journal:  J Neurol Neurosurg Psychiatry       Date:  2002-03       Impact factor: 10.154

6.  Dynamometer-based measure of spasticity confirms limited association between plantarflexor spasticity and walking function in persons with multiple sclerosis.

Authors:  Theodore R Kremer; Linda R Van Dillen; Joanne M Wagner
Journal:  J Rehabil Res Dev       Date:  2014

7.  Expression of scavenger receptor A on antigen presenting cells is important for CD4+ T-cells proliferation in EAE mouse model.

Authors:  Hilit Levy-Barazany; Dan Frenkel
Journal:  J Neuroinflammation       Date:  2012-06-07       Impact factor: 8.322

8.  Multiple sclerosis: overview of disease-modifying agents.

Authors:  Alessandro Finkelsztejn
Journal:  Perspect Medicin Chem       Date:  2014-10-05

9.  Microwave & magnetic (M2) proteomics reveals CNS-specific protein expression waves that precede clinical symptoms of experimental autoimmune encephalomyelitis.

Authors:  Itay Raphael; Swetha Mahesula; Anjali Purkar; David Black; Alexis Catala; Jonathon A L Gelfond; Thomas G Forsthuber; William E Haskins
Journal:  Sci Rep       Date:  2014-09-03       Impact factor: 4.379

10.  Quantifying gait impairment using an instrumented treadmill in people with multiple sclerosis.

Authors:  Alon Kalron; Zeevi Dvir; Lior Frid; Anat Achiron
Journal:  ISRN Neurol       Date:  2013-06-25
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