Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Delta(12)-prostaglandin J(2) is a potent inhibitor of influenza A virus replication.

Literature DB >> 10602750

Delta(12)-prostaglandin J(2) is a potent inhibitor of influenza A virus replication.

F Pica¹, A T Palamara, A Rossi, A De Marco, C Amici, M G Santoro.

Abstract

9-Deoxy-Delta(9),Delta(12)-13,14-dihydro-prostaglandin D(2) (Delta(12)-PGJ(2)), a natural cyclopentenone metabolite of prostaglandin D(2), is shown to possess therapeutic efficacy against influenza A virus A/PR8/34 (H1N1) infection in vitro and in vivo. The results indicate that the antiviral activity is associated with induction of cytoprotective heat shock proteins and suggest novel strategies for treatment of influenza virus infection.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2000 PMID： 10602750 PMCID： PMC89655 DOI： 10.1128/AAC.44.1.200-204.2000

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

16 in total

1. Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation.

Authors: A Rossi; G Elia; M G Santoro
Journal: Proc Natl Acad Sci U S A Date: 1997-01-21 Impact factor: 11.205

2. Mechanism of inhibition of herpes simplex virus replication by delta 7-prostaglandin A1 and delta 12-prostaglandin J2.

Authors: N Yamamoto; M Fukushima; T Tsurumi; K Maeno; Y Nishiyama
Journal: Biochem Biophys Res Commun Date: 1987-08-14 Impact factor: 3.575

3. Mutation of neuraminidase cysteine residues yields temperature-sensitive influenza viruses.

Authors: C F Basler; A García-Sastre; P Palese
Journal: J Virol Date: 1999-10 Impact factor: 5.103

4. 2-Cyclopenten-1-one, a new inducer of heat shock protein 70 with antiviral activity.

Authors: A Rossi; G Elia; M G Santoro
Journal: J Biol Chem Date: 1996-12-13 Impact factor: 5.157

5. Effects of dimethyl prostaglandin A1 on herpes simplex virus and human immunodeficiency virus replication.

Authors: M Hughes-Fulford; M S McGrath; D Hanks; S Erickson; L Pulliam
Journal: Antimicrob Agents Chemother Date: 1992-10 Impact factor: 5.191

6. Inhibition of poliovirus replication by prostaglandins A and J in human cells.

Authors: C Conti; P Mastromarino; P Tomao; A De Marco; F Pica; M G Santoro
Journal: Antimicrob Agents Chemother Date: 1996-02 Impact factor: 5.191

7. Inhibition of HIV-1 replication by cyclopentenone prostaglandins in acutely infected human cells. Evidence for a transcriptional block.

Authors: C Rozera; A Carattoli; A De Marco; C Amici; C Giorgi; M G Santoro
Journal: J Clin Invest Date: 1996-04-15 Impact factor: 14.808

8. Inhibition of vesicular stomatitis virus replication by delta 12-prostaglandin J2 is regulated at two separate levels and is associated with induction of stress protein synthesis.

Authors: F Pica; A De Marco; F De Cesare; M G Santoro
Journal: Antiviral Res Date: 1993-03 Impact factor: 5.970

9. Prevention and control of influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP). Centers for Disease Control and Prevention.

Authors:
Journal: MMWR Recomm Rep Date: 1996-05-03

10. Biochemical and clinical response of fulminant viral hepatitis to administration of prostaglandin E. A preliminary report.

Authors: S B Sinclair; P D Greig; L M Blendis; M Abecassis; E A Roberts; M J Phillips; R Cameron; G A Levy
Journal: J Clin Invest Date: 1989-10 Impact factor: 14.808

14 in total

1. Synergistic effect of nitazoxanide with neuraminidase inhibitors against influenza A viruses in vitro.

Authors: Giuseppe Belardo; Orlando Cenciarelli; Simone La Frazia; Jean Francois Rossignol; M Gabriella Santoro
Journal: Antimicrob Agents Chemother Date: 2014-12-01 Impact factor: 5.191

2. Persistent borna disease virus infection confers instability of HSP70 mRNA in glial cells during heat stress.

Authors: Makiko Yamashita; Wataru Kamitani; Hideyuki Yanai; Naohiro Ohtaki; Yohei Watanabe; Byeong-Jae Lee; Shoutaro Tsuji; Kazuyoshi Ikuta; Keizo Tomonaga
Journal: J Virol Date: 2005-02 Impact factor: 5.103

3. Antiviral properties, metabolism, and pharmacokinetics of a novel azolo-1,2,4-triazine-derived inhibitor of influenza A and B virus replication.

Authors: Inna Karpenko; Sergey Deev; Oleg Kiselev; Valerey Charushin; Vladimir Rusinov; Eugeney Ulomsky; Ella Deeva; Dmitry Yanvarev; Alexander Ivanov; Olga Smirnova; Sergey Kochetkov; Oleg Chupakhin; Marina Kukhanova
Journal: Antimicrob Agents Chemother Date: 2010-03-01 Impact factor: 5.191

4. Antiviral effects of geranylgeranylacetone: enhancement of MxA expression and phosphorylation of PKR during influenza virus infection.

Authors: Masako Unoshima; Hideo Iwasaka; Junko Eto; Yoshiko Takita-Sonoda; Takayuki Noguchi; Akira Nishizono
Journal: Antimicrob Agents Chemother Date: 2003-09 Impact factor: 5.191

5. Heat shock protein 70 is related to thermal inhibition of nuclear export of the influenza virus ribonucleoprotein complex.

Authors: Etsuko Hirayama; Hiromitsu Atagi; Akihiro Hiraki; Jeman Kim
Journal: J Virol Date: 2004-02 Impact factor: 5.103

6. Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level.

Authors: Jean François Rossignol; Simone La Frazia; Lucia Chiappa; Alessandra Ciucci; M Gabriella Santoro
Journal: J Biol Chem Date: 2009-07-28 Impact factor: 5.157

7. Bcl-2 expression and p38MAPK activity in cells infected with influenza A virus: impact on virally induced apoptosis and viral replication.

Authors: Lucia Nencioni; Giovanna De Chiara; Rossella Sgarbanti; Donatella Amatore; Katia Aquilano; Maria E Marcocci; Annalucia Serafino; Maria Torcia; Federico Cozzolino; Maria R Ciriolo; Enrico Garaci; Anna T Palamara
Journal: J Biol Chem Date: 2009-03-31 Impact factor: 5.157

8. 15d-Prostaglandin J2 induced reactive oxygen species-mediated apoptosis during experimental visceral leishmaniasis.

Authors: Preeti Vishwakarma; Naveen Parmar; Pawan Kumar Yadav; Pragya Chandrakar; Susanta Kar
Journal: J Mol Med (Berl) Date: 2016-02-01 Impact factor: 4.599

9. Transactivator protein BICP0 of bovine herpesvirus 1 (BHV-1) is blocked by prostaglandin D2 (PGD2), which points to a mechanism for PGD2-mediated inhibition of BHV-1 replication.

Authors: Okay Saydam; Carlos Abril; Bernd Vogt; Mathias Ackermann; Martin Schwyzer
Journal: J Virol Date: 2004-04 Impact factor: 5.103

10. Heat shock protein 70 inhibits the activity of Influenza A virus ribonucleoprotein and blocks the replication of virus in vitro and in vivo.

Authors: Gang Li; Junjie Zhang; Xiaomei Tong; Wenjun Liu; Xin Ye
Journal: PLoS One Date: 2011-02-24 Impact factor: 3.240