Literature DB >> 10602398

Immunobiology of the blood-brain barrier.

D W Miller1.   

Abstract

The brain microvessel endothelial cells (BMVEC) that form the blood-brain barrier are uniquely positioned to influence immune responses within the central nervous system. As the biological interface separating the blood from the brain extracellular fluid, BMVEC regulate the entry of leukocytes into the brain. In addition, through the release of various soluble factors that affect immune responses, BMVEC may modulate immune responses in the brain. This review addresses the interplay between the immune system and the blood-brain barrier as it relates to the regulation of CNS defense and immunity.

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Year:  1999        PMID： 10602398     DOI： 10.3109/13550289909021286

Source DB:  PubMed          Journal:  J Neurovirol        ISSN： 1355-0284            Impact factor:   2.643


  28 in total

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Review 8.  Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications.

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9.  Transport of human immunodeficiency virus type 1 pseudoviruses across the blood-brain barrier: role of envelope proteins and adsorptive endocytosis.

Authors:  W A Banks; E O Freed; K M Wolf; S M Robinson; M Franko; V B Kumar
Journal:  J Virol       Date:  2001-05       Impact factor: 5.103

Review 10.  Invasion of the central nervous system by intracellular bacteria.

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