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Literature DB >> 1060112

General model for nutritional responses of higher organisms.

Abstract

A general saturation equation is derived which is shown to describe a wide variety of nutrient-response relationships in higher organisms. Iterative multiple linear regression analysis is used to obtain least squares estimates of the constants defining theoretical nutrient-response curves. Curves thus generated accurately predict experimentally observed responses. From this treatment, response parameters are developed which are analogous to Vmax and Km of enzyme kinetics. It is proposed that this model be applied in evaluating nutritional requirements and in assessing the relative biological efficiency of nutrient sources.

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Year: 1975 PMID： 1060112 PMCID： PMC388714 DOI： 10.1073/pnas.72.11.4327

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

9 in total

1. PROTEIN UTILIZATION IN GROWING RATS. I. RELATIVE GROWTH INDEX AS A BIOASSAY PROCEDURE.

Authors: D M Hegsted; Y O Chang
Journal: J Nutr Date: 1965-02 Impact factor: 4.798

2. On the evaluation of the constants Vm and Km in enzyme reactions.

Authors: G S EADIE
Journal: Science Date: 1952-12-19 Impact factor: 47.728

3. On the evaluation of the constants Vm and KM in enzyme reactions.

Authors: B H J HOFSTEE
Journal: Science Date: 1952-09-26 Impact factor: 47.728

4. Estimation of the antihaemorrhagic vitamin.

Authors: H J Almquist; E Mecchi; A A Klose
Journal: Biochem J Date: 1938-11 Impact factor: 3.857

5. The Combinations of Haemoglobin with Oxygen and with Carbon Monoxide. I.

Authors: A V Hill
Journal: Biochem J Date: 1913-10 Impact factor: 3.857

6. A generalized mathematical model for the growth kinetics of Saccharomyces cerevisiae with experimental determination of parameters.

Authors: P Peringer; H Blachere; G Corrieu; A G Lane
Journal: Biotechnol Bioeng Date: 1974-04 Impact factor: 4.530

7. Efficiency of protein utilization in young rats at various levels of intake.

Authors: D M Hegsted; R Neff
Journal: J Nutr Date: 1970-10 Impact factor: 4.798

8. Amino acid retention and balance in the young rat fed varying levels of casein.

Authors: G E Bunce; K W King
Journal: J Nutr Date: 1969-06 Impact factor: 4.798

9. Utilization by the chick of vitamin A from different sources. I. Crystalline carotene, crystalline vitamin A acetate, and "black cod" liver oil.

Authors: F F CASTANO; R V BOUCHER; E W CALLENBACH
Journal: J Nutr Date: 1951-09 Impact factor: 4.798

9 in total

12 in total

General model for nutritional responses of higher organisms.

1. PROTEIN UTILIZATION IN GROWING RATS. I. RELATIVE GROWTH INDEX AS A BIOASSAY PROCEDURE.

2. On the evaluation of the constants Vm and Km in enzyme reactions.

3. On the evaluation of the constants Vm and KM in enzyme reactions.

4. Estimation of the antihaemorrhagic vitamin.

5. The Combinations of Haemoglobin with Oxygen and with Carbon Monoxide. I.

6. A generalized mathematical model for the growth kinetics of Saccharomyces cerevisiae with experimental determination of parameters.

7. Efficiency of protein utilization in young rats at various levels of intake.

8. Amino acid retention and balance in the young rat fed varying levels of casein.

9. Utilization by the chick of vitamin A from different sources. I. Crystalline carotene, crystalline vitamin A acetate, and "black cod" liver oil.

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