Literature DB >> 1060101

The extraordinary dielectric properties of biological materials and the action of enzymes.

H Fröhlich.   

Abstract

From very general theoretical considerations it is concluded that many biomolecules (i) should have metastable excited states with very high dipole moment, and (ii) should be capable of strongly excited giant dipole vibrations with frequencies near 10(11) Hz. Experimental evidence available so far seems to support these postulates. It is suggested that the two postulates should be of importance for the action of enzymes, and relevant experiments are proposed.

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Year:  1975        PMID: 1060101      PMCID: PMC388689          DOI: 10.1073/pnas.72.11.4211

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  5 in total

Review 1.  Hydration of proteins and polypeptides.

Authors:  I D Kuntz; W Kauzmann
Journal:  Adv Protein Chem       Date:  1974

2.  Long-lived conformation changes induced by electric impulses in biopolymers.

Authors:  E Neumann; A Katchalsky
Journal:  Proc Natl Acad Sci U S A       Date:  1972-04       Impact factor: 11.205

3.  Conformationally dependent low-frequency motions of proteins by laser Raman spectroscopy.

Authors:  K G Brown; S C Erfurth; E W Small; W L Peticolas
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

4.  Dielectric properties of hemoglobin and myoglobin. II. Dipole moment of sperm whale myoglobin.

Authors:  P Schlecht
Journal:  Biopolymers       Date:  1969       Impact factor: 2.505

5.  Dielectric dispersion in bovine serum albumen.

Authors:  E H Grant
Journal:  J Mol Biol       Date:  1966-08       Impact factor: 5.469

  5 in total
  26 in total

1.  Ionic wave propagation along actin filaments.

Authors:  J A Tuszyński; S Portet; J M Dixon; C Luxford; H F Cantiello
Journal:  Biophys J       Date:  2004-04       Impact factor: 4.033

2.  DNA Breathing Dynamics in the Presence of a Terahertz Field.

Authors:  B S Alexandrov; V Gelev; A R Bishop; A Usheva; K Ø Rasmussen
Journal:  Phys Lett A       Date:  2010-02-22       Impact factor: 2.654

Review 3.  How proteins come together in the plasma membrane and function in macromolecular assemblies: focus on receptor mosaics.

Authors:  Luigi F Agnati; Diego Guidolin; Susanna Genedani; Sergi Ferré; Albertino Bigiani; Amina S Woods; Kjell Fuxe
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

4.  An observation concerning electronically excited retinal.

Authors:  J Simons
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

Review 5.  Living systems are tonically inhibited, autonomous optimizers, and disinhibition coupled to variability generation is their major organizing principle: inhibitory command-control at levels of membrane, genome, metabolism, brain, and society.

Authors:  E Roberts
Journal:  Neurochem Res       Date:  1991-03       Impact factor: 3.996

6.  Limit cycle model for brain waves.

Authors:  F Kaiser
Journal:  Biol Cybern       Date:  1977-10-03       Impact factor: 2.086

7.  Thermal-stimulated pressure and current studies of bound water in lysozyme.

Authors:  S Celaschi; S Mascarenhas
Journal:  Biophys J       Date:  1977-11       Impact factor: 4.033

8.  Effect of microwave radiation on inactivation of Clostridium sporogenes (PA 3679) spores.

Authors:  B A Welt; C H Tong; J L Rossen; D B Lund
Journal:  Appl Environ Microbiol       Date:  1994-02       Impact factor: 4.792

Review 9.  Cytoskeletal involvement in neuronal learning: a review.

Authors:  J Dayhoff; S Hameroff; R Lahoz-Beltra; C E Swenberg
Journal:  Eur Biophys J       Date:  1994       Impact factor: 1.733

10.  On a model and the kinetics of photo-enhanced enzyme reactions.

Authors:  D Bhaumik; K Bhaumik; A K Ray; B Dutta-Roy
Journal:  Bull Math Biol       Date:  1978       Impact factor: 1.758

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