Literature DB >> 10597786

Effect of the worldwide epidemic on HIV prevalence in the United Kingdom: record linkage in anonymous neonatal seroprevalence surveys.

A E Ades1, J Walker, B Botting, S Parker, D Cubitt, R Jones.   

Abstract

OBJECTIVE: To assess the impact of the worldwide HIV/AIDS epidemic on the prevalence of HIV in women in the United Kingdom (UK), particularly in the large immigrant and ethnic minority communities.
METHOD: Unlinked anonymous neonatal seroprevalence survey with electronic record linkage of data from child health computers (maternal age and ethnic status) and birth registration (parent's country of birth).
RESULTS: Of a total 137456 samples collected in 1997-1998, 188 (0.14%) were anti-HIV-1 seropositive. Seroprevalence was highest in women born in East Africa (2.3%) and Central Africa (1.9%). 76.4% of seropositive newborns were delivered to mothers born in sub-Saharan Africa; a further 6.0% had fathers from sub-Saharan Africa. However, there was little evidence of HIV in women born in Southern Asia [prevalence 0.0081%; 95% confidence interval (CI) 0-0.04], and none within UK-born Asian communities. Prevalence among the UK-born Black African community was low (0.14%; 95% CI 0-0.6). Among infants with both parents known to be born in the UK, seroprevalence was 0.023% (95% CI 0.01-0.04) in London, and zero (95% CI 0-0.007) in non-Metropolitan areas. Irrespective of mother's region of birth, seroprevalence was 4.2 times higher (95% CI 3.0-5.8) in newborns whose father's details were not recorded at birth registration, a marker for single unsupported mothers.
CONCLUSION: The risk of HIV among pregnant women from sub-Saharan Africa has been recognized. However, in southern England, HIV is very rare in women from Southern Asia and in UK-born women in ethnic minority communities, in spite of cultural and travel ties to high-prevalence countries. Data linkage in anonymous surveys assists in monitoring the impact of the worldwide epidemic on prevalence and incidence locally.

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Year:  1999        PMID: 10597786     DOI: 10.1097/00002030-199912030-00016

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  4 in total

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Authors:  Nina T Harawa; Trista A Bingham; Susan D Cochran; Sander Greenland; William E Cunningham
Journal:  Am J Public Health       Date:  2002-12       Impact factor: 9.308

2.  Human T cell leukaemia/lymphoma virus infection in pregnant women in the United Kingdom: population study.

Authors:  A E Ades; S Parker; J Walker; M Edginton; G P Taylor; J N Weber
Journal:  BMJ       Date:  2000-06-03

3.  Analysis of rubella antibody distribution from newborn dried blood spots using finite mixture models.

Authors:  P Hardelid; D Williams; C Dezateux; P A Tookey; C S Peckham; W D Cubitt; M Cortina-Borja
Journal:  Epidemiol Infect       Date:  2008-02-25       Impact factor: 2.451

4.  HIV infection among people of foreign origin voluntarily tested in Spain. A comparison with national subjects.

Authors:  Jesús Castilla; Paz Sobrino; Julia del Amo
Journal:  Sex Transm Infect       Date:  2002-08       Impact factor: 3.519

  4 in total

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