Literature DB >> 10596894

A procedure for the preparation of GM3 ganglioside from GM1-lactone.

L Mauri1, R Casellato, G Kirschner, S Sonnino.   

Abstract

A simple procedure is described for preparing GM3 ganglioside, from a few milligrams to grams, from GM1-lactone (Sonnino et al., (1985) Glycoconjugate J 2: 343-54) [1]. The synthesis was carried out under the following optimal conditions: 30 mM GM1-lactone in 0.25 M H2SO4 in DMSO, 30 min, 70 degrees C, nitrogen atmosphere, strong stirring. The yield of GM3 was 55%. The procedure applied to milligram amounts of GD1b-dilactone gave GD3 ganglioside.

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Year:  1999        PMID： 10596894     DOI： 10.1023/a:1007072203345

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  25 in total

1.  Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method.

Authors:  L SVENNERHOLM
Journal:  Biochim Biophys Acta       Date:  1957-06

2.  Significant immunosuppressive effect of ganglioside GM3 in organ transplantation.

Authors:  M Hachida; R Irie; D L Morton
Journal:  Transplant Proc       Date:  1990-08       Impact factor: 1.066

Review 3.  The role of sphingolipids in the process of signal transduction.

Authors:  L Riboni; P Viani; R Bassi; A Prinetti; G Tettamanti
Journal:  Prog Lipid Res       Date:  1997-09       Impact factor: 16.195

4.  On the structure of two new gangliosides from beef brain.

Authors:  R Ghidoni; S Sonnino; G Tettamanti; H Wiegandt; V Zambotti
Journal:  J Neurochem       Date:  1976-08       Impact factor: 5.372

5.  A new procedure for the extraction, purification and fractionation of brain gangliosides.

Authors:  G Tettamanti; F Bonali; S Marchesini; V Zambotti
Journal:  Biochim Biophys Acta       Date:  1973-01-19

Review 6.  Structure and function of sphingoglycolipids in transmembrane signalling and cell-cell interactions.

Authors:  S Hakomori
Journal:  Biochem Soc Trans       Date:  1993-08       Impact factor: 5.407

7.  Ganglioside designation.

Authors:  L Svennerholm
Journal:  Adv Exp Med Biol       Date:  1980       Impact factor: 2.622

8.  Synthesis, structure, and conformation of the dilactone derivative of GD1b ganglioside.

Authors:  G Fronza; G Kirschner; D Acquotti; S Sonnino
Journal:  Carbohydr Res       Date:  1989-12-21       Impact factor: 2.104

9.  Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor.

Authors:  E G Bremer; J Schlessinger; S Hakomori
Journal:  J Biol Chem       Date:  1986-02-15       Impact factor: 5.157

10.  Binding of interleukin 2 to gangliosides.

Authors:  J Parker; G Caldini; C Krishnamurti; P B Ahrens; H Ankel
Journal:  FEBS Lett       Date:  1984-05-21       Impact factor: 4.124
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  4 in total

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Journal:  Glycoconj J       Date:  2002-03       Impact factor: 2.916

2.  Involvement of very long fatty acid-containing lactosylceramide in lactosylceramide-mediated superoxide generation and migration in neutrophils.

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Journal:  Glycoconj J       Date:  2007-11-28       Impact factor: 2.916

3.  N-glycolyl GM1 ganglioside as a receptor for simian virus 40.

Authors:  Maria A Campanero-Rhodes; Alicia Smith; Wengang Chai; Sandro Sonnino; Laura Mauri; Robert A Childs; Yibing Zhang; Helge Ewers; Ari Helenius; Anne Imberty; Ten Feizi
Journal:  J Virol       Date:  2007-09-12       Impact factor: 5.103

4.  Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.

Authors:  Hirotaka Kanoh; Takahiro Nitta; Shinji Go; Kei-Ichiro Inamori; Lucas Veillon; Wataru Nihei; Mayu Fujii; Kazuya Kabayama; Atsushi Shimoyama; Koichi Fukase; Umeharu Ohto; Toshiyuki Shimizu; Taku Watanabe; Hiroki Shindo; Sorama Aoki; Kenichi Sato; Mika Nagasaki; Yutaka Yatomi; Naoko Komura; Hiromune Ando; Hideharu Ishida; Makoto Kiso; Yoshihiro Natori; Yuichi Yoshimura; Asia Zonca; Anna Cattaneo; Marilena Letizia; Maria Ciampa; Laura Mauri; Alessandro Prinetti; Sandro Sonnino; Akemi Suzuki; Jin-Ichi Inokuchi
Journal:  EMBO J       Date:  2020-05-07       Impact factor: 11.598
  4 in total

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