Literature DB >> 10596774

Repetitive high G exposure is associated with increased occurrence of cardiac valvular regurgitation.

D S Martin1, D S D'Aunno, M L Wood, D A South.   

Abstract

BACKGROUND: Exposure to repeated high +Gz loads and the methods to prevent loss of consciousness cause unique stresses on the cardiovascular system. The purpose of this study was to determine if the +Gz environment is associated with an increased occurrence of valvular regurgitation in pilots of high performance aircraft.
METHODS: There were 247 subjects who were divided into pilot (n = 46) and non-pilot (n = 201) groups. Pilots were defined as those individuals who had flown at least 1000 h in high performance aircraft. The echocardiographic data of these subjects were examined retrospectively.
RESULTS: We found a statistically significant association between pulmonic insufficiency and exposure to high +Gz stress in pilots vs. non-pilots (chi2 = 13.09, p = 0.0002). In addition, there was a greater incidence of tricuspid regurgitation (chi2 = 4.97, p = 0.025) and concurrent pulmonic insufficiency and tricuspid regurgitation (chi2 = 14.1, p = 0.0002) in the pilot group.
CONCLUSIONS: There is a direct relationship between repetitive exposure to a +Gz environment and pulmonic insufficiency, tricuspid regurgitation, or concurrent pulmonic insufficiency and tricuspid regurgitation. This may be secondary to the transient increase in right ventricular pressure due to acceleration forces or straining maneuvers utilized to prevent or postpone +Gz induced loss of consciousness (G-LOC).

Entities:  

Mesh:

Year:  1999        PMID: 10596774

Source DB:  PubMed          Journal:  Aviat Space Environ Med        ISSN: 0095-6562


  4 in total

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Journal:  J Physiol Sci       Date:  2013-09-03       Impact factor: 2.781

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Journal:  World J Gastroenterol       Date:  2015-06-07       Impact factor: 5.742

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Authors:  Huilan Luo; Yongsheng Chen; Junhua Wang
Journal:  J Cardiovasc Dis Res       Date:  2010-04

4.  Endoplasmic Reticulum Is Involved in Myocardial Injury in a Miniature Swine Model of Coronary Artery Stenosis Exposed to Acceleration-Associated Stress.

Authors:  Haitao Zhang; Meng Chai; Chaozhong Liu; Jinjin Sun; Congchun Huang; Xinya Yu; Yi Tian; Huilan Luo
Journal:  PLoS One       Date:  2015-07-13       Impact factor: 3.240

  4 in total

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