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Literature DB >> 10595905

Tau pathology generated by overexpression of tau.

I Grundke-Iqbal¹, K Iqbal.

Abstract

Entities: Gene

Mesh：

Substances：
tau Proteins

Year: 1999 PMID： 10595905 PMCID： PMC1866922 DOI： 10.1016/S0002-9440(10)65494-6

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

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72 in total

1. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein.

Authors: K Spittaels; C Van den Haute; J Van Dorpe; K Bruynseels; K Vandezande; I Laenen; H Geerts; M Mercken; R Sciot; A Van Lommel; R Loos; F Van Leuven
Journal: Am J Pathol Date: 1999-12 Impact factor: 4.307

2. Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules.

Authors: A Sengupta; J Kabat; M Novak; Q Wu; I Grundke-Iqbal; K Iqbal
Journal: Arch Biochem Biophys Date: 1998-09-15 Impact factor: 4.013

3. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

Authors: M Hong; V Zhukareva; V Vogelsberg-Ragaglia; Z Wszolek; L Reed; B I Miller; D H Geschwind; T D Bird; D McKeel; A Goate; J C Morris; K C Wilhelmsen; G D Schellenberg; J Q Trojanowski; V M Lee
Journal: Science Date: 1998-12-04 Impact factor: 47.728

4. Progressive dendritic changes in the aging human limbic system.

Authors: M E Scheibel; R D Lindsay; U Tomiyasu; A B Scheibel
Journal: Exp Neurol Date: 1976-11 Impact factor: 5.330

5. Observations on the brains of demented old people.

Authors: B E Tomlinson; G Blessed; M Roth
Journal: J Neurol Sci Date: 1970-09 Impact factor: 3.181

6. Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly.

Authors: M Hasegawa; M J Smith; M Goedert
Journal: FEBS Lett Date: 1998-10-23 Impact factor: 4.124

7. Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

Authors: D Blacker; M A Wilcox; N M Laird; L Rodes; S M Horvath; R C Go; R Perry; B Watson; S S Bassett; M G McInnis; M S Albert; B T Hyman; R E Tanzi
Journal: Nat Genet Date: 1998-08 Impact factor: 38.330

8. Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution.

Authors: P Friedhoff; A Schneider; E M Mandelkow; E Mandelkow
Journal: Biochemistry Date: 1998-07-14 Impact factor: 3.162

9. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity.

Authors: C Geula; C K Wu; D Saroff; A Lorenzo; M Yuan; B A Yankner
Journal: Nat Med Date: 1998-07 Impact factor: 53.440

10. Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease.

Authors: J P Brion; G Tremp; J N Octave
Journal: Am J Pathol Date: 1999-01 Impact factor: 4.307

5 in total

Review 1. The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease.

Authors: Laura J Blair; Jeremy D Baker; Jonathan J Sabbagh; Chad A Dickey
Journal: J Neurochem Date: 2015-02-24 Impact factor: 5.372

2. Biochemical studies in Normal Pressure Hydrocephalus (NPH) patients: change in CSF levels of amyloid precursor protein (APP), amyloid-beta (Aβ) peptide and phospho-tau.

Authors: Balmiki Ray; Patricio F Reyes; Debomoy K Lahiri
Journal: J Psychiatr Res Date: 2010-09-09 Impact factor: 4.791