| Literature DB >> 10594913 |
M F Meek1, J R Dijkstra, W F Den Dunnen, J Ijkema-Paassen, J M Schakenraad, A Gramsbergen, P H Robinson.
Abstract
The aim of this study was to compare functional nerve recovery after reconstruction with a biodegradable p(DLLA-epsilon-CL) nerve guide filled with modified denatured muscle tissue (MDMT), or an autologous nerve graft. We evaluated nerve recovery using walking track analysis (measurement of the sciatic function index [SFI]) and electrostimulation tests. Functional nerve recovery after reconstruction with a biodegradable p(DLLA-epsilon-CL) nerve guide filled with MDMT was faster when compared with nerve reconstruction using an autologous nerve graft. We conclude that in case of a short nerve gap in the rat, reconstruction can best be carried out using a p(DLLA-epsilon-CL) biodegradable nerve guide filled with MDMT. Copyright 1999 Wiley-Liss, Inc.Entities:
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Year: 1999 PMID： 10594913 DOI： 10.1002/(sici)1098-2752(1999)19:8<381::aid-micr6>3.0.co;2-7
Source DB: PubMed Journal: Microsurgery ISSN： 0738-1085 Impact factor: 2.425