Literature DB >> 10594364

The presence of an endogenous endo-D-arabinase in Mycobacterium smegmatis and characterization of its oligoarabinoside product.

Y Xin1, Y Huang, M R McNeil.   

Abstract

Endogenous mycobacterial endo-D-arabinase activity, which degrades cell wall polysaccharide arabinogalactan, was found in Mycobacterium smegmatis. The arabinan product contains 20-30 arabinosyl residues but no galactofuranosyl residues. Recognition of this endogenous activity results in the possibility of developing antituberculosis drugs that do not require bacterial growth for activity.

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Year:  1999        PMID: 10594364     DOI: 10.1016/s0304-4165(99)00204-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  7 in total

1.  Exposure of mycobacteria to cell wall-inhibitory drugs decreases production of arabinoglycerolipid related to Mycolyl-arabinogalactan-peptidoglycan metabolism.

Authors:  Yoann Rombouts; Belinda Brust; Anil K Ojha; Emmanuel Maes; Bernadette Coddeville; Elisabeth Elass-Rochard; Laurent Kremer; Yann Guerardel
Journal:  J Biol Chem       Date:  2012-02-07       Impact factor: 5.157

2.  Sequencing of oligoarabinosyl units released from mycobacterial arabinogalactan by endogenous arabinanase: identification of distinctive and novel structural motifs.

Authors:  Arwen Lee; Sz-Wei Wu; Michael S Scherman; Jordi B Torrelles; Delphi Chatterjee; Michael R McNeil; Kay-Hooi Khoo
Journal:  Biochemistry       Date:  2006-12-07       Impact factor: 3.162

3.  The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan.

Authors:  Lin Shen; Albertus Viljoen; Sydney Villaume; Maju Joe; Iman Halloum; Loïc Chêne; Alexandre Méry; Emeline Fabre; Kaoru Takegawa; Todd L Lowary; Stéphane P Vincent; Laurent Kremer; Yann Guérardel; Christophe Mariller
Journal:  J Biol Chem       Date:  2020-02-27       Impact factor: 5.157

4.  Purification and characterization of an endo-D: -arabinase produced by cellulomonas.

Authors:  Ming-Zhong Sun; Xiao-Ying Zhang; Yi Xin
Journal:  Protein J       Date:  2012-01       Impact factor: 2.371

5.  Development of a quantitative assay for mycobacterial endogenous arabinase and ensuing studies of arabinase levels and arabinan metabolism in Mycobacterium smegmatis.

Authors:  Xu Dong; Suresh Bhamidi; Michael Scherman; Yi Xin; Michael R McNeil
Journal:  Appl Environ Microbiol       Date:  2006-04       Impact factor: 4.792

6.  The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions.

Authors:  Keriann M Backus; Michael A Dolan; Conor S Barry; Maju Joe; Peter McPhie; Helena I M Boshoff; Todd L Lowary; Benjamin G Davis; Clifton E Barry
Journal:  J Biol Chem       Date:  2014-07-14       Impact factor: 5.157

Review 7.  Synthesis and recycling of the mycobacterial cell envelope.

Authors:  Katherine A Abrahams; Gurdyal S Besra
Journal:  Curr Opin Microbiol       Date:  2021-02-18       Impact factor: 7.934

  7 in total

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