| Literature DB >> 10592308 |
E Kohmura1, T Yuguchi, T Yoshimine, T Fujinaka, N Koseki, A Sano, A Kishino, C Nakayama, T Sakaki, M Nonaka, O Takemoto, T Hayakawa.
Abstract
We investigated the effect of BDNF mini-pellet on the GAP-43 mRNA expression and functional status of facial nerve in a rat model of facial nerve transection and immediate repair. The facial function started to recover at 17 days in the placebo group and 14 days in the BDNF group. BDNF group had shorter period of increased GAP-43 mRNA expression than the placebo group. Topically applied BDNF may accelerate the facial nerve regeneration.Entities:
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Year: 1999 PMID: 10592308 DOI: 10.1016/s0006-8993(99)02163-0
Source DB: PubMed Journal: Brain Res ISSN: 0006-8993 Impact factor: 3.252