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Literature DB >> 10592180

The EcoCyc and MetaCyc databases.

P D Karp¹, M Riley, M Saier, I T Paulsen, S M Paley, A Pellegrini-Toole.

Abstract

EcoCyc is an organism-specific Pathway/Genome Database that describes the metabolic and signal-transduction pathways of Escherichia coli, its enzymes, and-a new addition-its transport proteins. MetaCyc is a new metabolic-pathway database that describes pathways and enzymes of many different organisms, with a microbial focus. Both databases are queried using the Pathway Tools graphical user interface, which provides a wide variety of query operations and visualization tools. EcoCyc and MetaCyc are available at http://ecocyc.PangeaSystems.com/ecocyc/

Entities: Species

Mesh：

Year: 2000 PMID： 10592180 PMCID： PMC102475 DOI： 10.1093/nar/28.1.56

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

3 in total

1. Integrated pathway-genome databases and their role in drug discovery.

Authors: P D Karp; M Krummenacker; S Paley; J Wagg
Journal: Trends Biotechnol Date: 1999-07 Impact factor: 19.536

2. Integrated access to metabolic and genomic data.

Authors: P D Karp; S Paley
Journal: J Comput Biol Date: 1996 Impact factor: 1.479

3. Microbial genome analyses: global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities.

Authors: I T Paulsen; M K Sliwinski; M H Saier
Journal: J Mol Biol Date: 1998-04-03 Impact factor: 5.469

3 in total

54 in total

1. The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities.

Authors: J S Edwards; B O Palsson
Journal: Proc Natl Acad Sci U S A Date: 2000-05-09 Impact factor: 11.205

Review 2. Metabolic pathway analysis in trypanosomes and malaria parasites.

Authors: Alan H Fairlamb
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2002-01-29 Impact factor: 6.237

3. Divergence of function in sequence-related groups of Escherichia coli proteins.

Authors: L A Nahum; M Riley
Journal: Genome Res Date: 2001-08 Impact factor: 9.043

4. Creating the gene ontology resource: design and implementation.

Authors:
Journal: Genome Res Date: 2001-08 Impact factor: 9.043

5. Functional versatility and molecular diversity of the metabolic map of Escherichia coli.

Authors: S Tsoka; C A Ouzounis
Journal: Genome Res Date: 2001-09 Impact factor: 9.043

6. The phylogenetic extent of metabolic enzymes and pathways.

Authors: José Manuel Peregrin-Alvarez; Sophia Tsoka; Christos A Ouzounis
Journal: Genome Res Date: 2003-03 Impact factor: 9.043

7. A semiautomated approach to gene discovery through expressed sequence tag data mining: discovery of new human transporter genes.

Authors: Shoshana Brown; Jean L Chang; Wolfgang Sadée; Patricia C Babbitt
Journal: AAPS PharmSci Date: 2003

8. PipeOnline 2.0: automated EST processing and functional data sorting.

Authors: Patricia Ayoubi; Xiaojing Jin; Saul Leite; Xianghui Liu; Jeson Martajaja; Abdurashid Abduraham; Qiaolan Wan; Wei Yan; Eduardo Misawa; Rolf A Prade
Journal: Nucleic Acids Res Date: 2002-11-01 Impact factor: 16.971

Review 9. Computational prediction of protein-protein interactions.

Authors: Lucy Skrabanek; Harpreet K Saini; Gary D Bader; Anton J Enright
Journal: Mol Biotechnol Date: 2007-08-14 Impact factor: 2.695

10. Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery.

Authors: Iwei Yeh; Theodor Hanekamp; Sophia Tsoka; Peter D Karp; Russ B Altman
Journal: Genome Res Date: 2004-04-12 Impact factor: 9.043