Literature DB >> 10591504

A rapid latex agglutination test for detection of leptospiral antibodies.

P Ramadass1, B Samuel, K Nachimuthu.   

Abstract

A rapid semi-quantitative latex agglutination test (LAT) has been standardized for the detection of leptospiral antibodies in serum samples of man and animals. The efficacy of the LAT was compared with the plate enzyme linked immunosorbent assay (ELISA). A total of 276 human serum samples were analyzed by both LAT and ELISA and percentage positives were 84.8 and 85.9%, respectively. Similarly, of 65 animal samples tested, 63.1 and 69.2% positivity were observed in LAT and ELISA, respectively. Even though the ELISA test was slightly more sensitive than LAT, the rapidity, simplicity and economics of the LAT were found to fulfill the requirements of a screening test for leptospiral antibodies.

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Year:  1999        PMID： 10591504     DOI： 10.1016/s0378-1135(99)00133-9

Source DB:  PubMed          Journal:  Vet Microbiol        ISSN： 0378-1135            Impact factor:   3.293


  6 in total

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Authors:  T M A Senthilkumar; M Subathra; P Ramadass; V Ramaswamy
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2.  Comparative evaluation of recombinant LigB protein and heat-killed antigen-based latex agglutination test with microscopic agglutination test for diagnosis of bovine leptospirosis.

Authors:  Mohandoss Nagalingam; Sushma Rahim Assadi Thirumalesh; Triveni Kalleshamurthy; Nakkala Niharika; Vinayagamurthy Balamurugan; Rajeswari Shome; Pinaki Prasad Sengupta; Bibek Ranjan Shome; Krishnamsetty Prabhudas; Habibur Rahman
Journal:  Trop Anim Health Prod       Date:  2015-06-12       Impact factor: 1.559

3.  Two methods for rapid serological diagnosis of acute leptospirosis.

Authors:  P N Levett; S L Branch; C U Whittington; C N Edwards; H Paxton
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

4.  Recombinant antigen-based latex agglutination test for rapid serodiagnosis of leptospirosis.

Authors:  S Dey; C Madhan Mohan; P Ramadass; K Nachimuthu
Journal:  Vet Res Commun       Date:  2006-12-20       Impact factor: 2.459

5.  Synthesis of multivalent tuberculosis and Leishmania-associated capping carbohydrates reveals structure-dependent responses allowing immune evasion.

Authors:  Eun-Ho Song; Alex O Osanya; Christine A Petersen; Nicola L B Pohl
Journal:  J Am Chem Soc       Date:  2010-08-25       Impact factor: 15.419

6.  Lipopolysaccharide Specific Immunochromatography Based Lateral Flow Assay for Serogroup Specific Diagnosis of Leptospirosis in India.

Authors:  Shanmugam Vanithamani; Santhanam Shanmughapriya; Ramasamy Narayanan; Veerapandian Raja; Murugesan Kanagavel; Karikalacholan Sivasankari; Kalimuthusamy Natarajaseenivasan
Journal:  PLoS One       Date:  2015-09-04       Impact factor: 3.240
  6 in total

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