Literature DB >> 10590759

Methylmercury: a new look at the risks.

K R Mahaffey1.   

Abstract

In the US, exposure to methylmercury, a neurotoxin, occurs primarily through consumption of fish. Data from recent studies assessing the health impact of methylmercury exposure due to consumption of fish and other sources in the aquatic food web (shellfish, crustacea, and marine mammals) suggest adverse effects at levels previously considered safe. There is substantial variation in human methylmercury exposure based on differences in the frequency and amount of fish consumed and in the fish's mercury concentration. Although virtually all fish and other seafood contain at least trace amounts of methylmercury, large predatory fish species have the highest concentrations. Concerns have been expressed about mercury exposure levels in the US, particularly among sensitive populations, and discussions are underway about the standards used by various federal agencies to protect the public. In the 1997 Mercury Study Report to Congress, the US Environmental Protection Agency summarized the current state of knowledge on methylmercury's effects on the health of humans and wildlife; sources of mercury; and how mercury is distributed in the environment. This article summarizes some of the major findings in the Report to Congress and identifies issues of concern to the public health community.

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Year:  1999        PMID: 10590759      PMCID: PMC1308510     

Source DB:  PubMed          Journal:  Public Health Rep        ISSN: 0033-3549            Impact factor:   2.792


  32 in total

1.  Methylmercury poisoning in Iraq.

Authors:  F Bakir; S F Damluji; L Amin-Zaki; M Murtadha; A Khalidi; N Y al-Rawi; S Tikriti; H I Dahahir; T W Clarkson; J C Smith; R A Doherty
Journal:  Science       Date:  1973-07-20       Impact factor: 47.728

2.  The relationship between blood levels and dose of methylmercury in man.

Authors:  T G Kershaw; T W Clarkson; P H Dhahir
Journal:  Arch Environ Health       Date:  1980 Jan-Feb

3.  Mercury and Mink. II. Experimental methyl mercury intoxication.

Authors:  G Wobeser; N O Nielsen; B Schiefer
Journal:  Can J Comp Med       Date:  1976-01

4.  Hair methylmercury levels in U.S. women.

Authors:  J C Smith; P V Allen; R Von Burg
Journal:  Arch Environ Health       Date:  1997 Nov-Dec

5.  Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury.

Authors:  P Grandjean; P Weihe; R F White; F Debes; S Araki; K Yokoyama; K Murata; N Sørensen; R Dahl; P J Jørgensen
Journal:  Neurotoxicol Teratol       Date:  1997 Nov-Dec       Impact factor: 3.763

6.  Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: outcomes at 66 months of age in the Seychelles Child Development Study.

Authors:  P W Davidson; G J Myers; C Cox; C Axtell; C Shamlaye; J Sloane-Reeves; E Cernichiari; L Needham; A Choi; Y Wang; M Berlin; T W Clarkson
Journal:  JAMA       Date:  1998-08-26       Impact factor: 56.272

7.  Hereditary analysis of the strain difference of methylmercury distribution in mice.

Authors:  R Doi; M Tagawa; H Tanaka; K Nakaya
Journal:  Toxicol Appl Pharmacol       Date:  1983-07       Impact factor: 4.219

8.  National estimates of blood lead levels: United States, 1976-1980: association with selected demographic and socioeconomic factors.

Authors:  K R Mahaffey; J L Annest; J Roberts; R S Murphy
Journal:  N Engl J Med       Date:  1982-09-02       Impact factor: 91.245

9.  Deficits in psychologic and classroom performance of children with elevated dentine lead levels.

Authors:  H L Needleman; C Gunnoe; A Leviton; R Reed; H Peresie; C Maher; P Barrett
Journal:  N Engl J Med       Date:  1979-03-29       Impact factor: 91.245

10.  Lead exposure and intelligence in 7-year-old children: the Yugoslavia Prospective Study.

Authors:  G A Wasserman; X Liu; N J Lolacono; P Factor-Litvak; J K Kline; D Popovac; N Morina; A Musabegovic; N Vrenezi; S Capuni-Paracka; V Lekic; E Preteni-Redjepi; S Hadzialjevic; V Slavkovich; J H Graziano
Journal:  Environ Health Perspect       Date:  1997-09       Impact factor: 9.031

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  16 in total

1.  Methylmercury exposure: fishing for answers.

Authors:  E Weir
Journal:  CMAJ       Date:  2001-07-24       Impact factor: 8.262

2.  Risk assessment for methylmercury in fish from the Songhua River, China: 30 years after mercury-containing wastewater outfalls were eliminated.

Authors:  Hui Zhu; Baixing Yan; Huicong Cao; Lixia Wang
Journal:  Environ Monit Assess       Date:  2011-03-09       Impact factor: 2.513

3.  Long-term dynamics of total mercury in surficial bottom sediments of the Volga River's reservoir in central Russia.

Authors:  Yury G Udodenko; Viktor T Komov; Viktor V Zakonnov
Journal:  Environ Monit Assess       Date:  2018-03-07       Impact factor: 2.513

4.  Environmental risks and children's health: what can PRAMS tell us?

Authors:  Katrina Smith Korfmacher; Barbara J Suter; Xueya Cai; Susan A Brownson; Ann M Dozier
Journal:  Matern Child Health J       Date:  2014-07

Review 5.  Thiomersal in vaccines: balancing the risk of adverse effects with the risk of vaccine-preventable disease.

Authors:  Mark Bigham; Ray Copes
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

6.  Associations of blood and urinary mercury with hypertension in U.S. adults: the NHANES 2003-2006.

Authors:  Sung Kyun Park; Sunghee Lee; Niladri Basu; Alfred Franzblau
Journal:  Environ Res       Date:  2013-03-06       Impact factor: 6.498

7.  Mercury, vaccines, and autism: one controversy, three histories.

Authors:  Jeffrey P Baker
Journal:  Am J Public Health       Date:  2008-01-02       Impact factor: 9.308

8.  Prenatal exposure to dental amalgam and risk of symptoms of attention-deficit and hyperactivity disorder (ADHD).

Authors:  Gunvor B Lygre; Heidi Aase; Kjell Haug; Stein A Lie; Lars Björkman
Journal:  Community Dent Oral Epidemiol       Date:  2018-08-07       Impact factor: 3.383

9.  Mercury exposure: medical and public health issues.

Authors:  Kathryn R Mahaffey
Journal:  Trans Am Clin Climatol Assoc       Date:  2005

10.  Mercury levels in high-end consumers of fish.

Authors:  Jane M Hightower; Dan Moore
Journal:  Environ Health Perspect       Date:  2003-04       Impact factor: 9.031

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