| Literature DB >> 10590290 |
K O Buabeng1, A R Mackenzie, R B Laing, I Cook, B Jappy, I M Gould.
Abstract
Fifty-five patients who received od gentamicin were studied. The protocol for od gentamicin was followed in 23/55 (48%). Cure rates were 22/23 (96%) when the protocol was followed and 24/32 (75%) when not followed (P = 0.06). Toxicity was more common in those in whom the protocol was not followed (9/32; 28%) than in those in whom it was followed (1/23; 4%) (P< 0.05). The number needed to treat with the protocol to produce one additional cure was 4.84 (95% CI 2.64 to 28.66) and the number needed to treat to prevent one case of toxicity was 3.61 (95% CI 2.16 to 10.99).Entities:
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Year: 1999 PMID： 10590290 DOI： 10.1093/jac/44.6.843
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790