Literature DB >> 10589994

Role of an ABC importer in mycobacterial drug resistance.

P K Chakraborti1, K Bhatt, S K Banerjee, P Misra.   

Abstract

Phosphate specific transporter (Pst) in bacteria is involved in phosphate transport. Pst is a multisubunit system which belongs to the ABC family of transporters. The import function of this transporter is known to be operative at media phosphate concentrations below the millimolar range. However, we found amplification of this transporter in a laboratory generated ciprofloxacin resistant Mycobacterium smegmatis colony (CIPr) which was grown in a condition when phosphate scavenging function of this operon was inoperative. Our results therefore argue the role of this ABC importer in conferring high level of fluoroquinolone resistance in CIPr.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10589994     DOI： 10.1023/a:1020598324663

Source DB:  PubMed          Journal:  Biosci Rep        ISSN： 0144-8463            Impact factor:   3.840


  5 in total

Review 1.  Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria.

Authors:  Jacek Lubelski; Wil N Konings; Arnold J M Driessen
Journal:  Microbiol Mol Biol Rev       Date:  2007-09       Impact factor: 11.056

2.  Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure.

Authors:  Leah Mwai; Abdi Diriye; Victor Masseno; Steven Muriithi; Theresa Feltwell; Jennifer Musyoki; Jacob Lemieux; Avi Feller; Gunnar R Mair; Kevin Marsh; Chris Newbold; Alexis Nzila; Céline K Carret
Journal:  PLoS One       Date:  2012-02-27       Impact factor: 3.240

3.  Antimicrobial and Amyloidogenic Activity of Peptides Synthesized on the Basis of the Ribosomal S1 Protein from Thermus Thermophilus.

Authors:  Stanislav R Kurpe; Sergei Yu Grishin; Alexey K Surin; Olga M Selivanova; Roman S Fadeev; Ulyana F Dzhus; Elena Yu Gorbunova; Leila G Mustaeva; Vyacheslav N Azev; Oxana V Galzitskaya
Journal:  Int J Mol Sci       Date:  2020-09-02       Impact factor: 5.923

4.  Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PfMRP) alters its fitness and transport of antimalarial drugs and glutathione.

Authors:  Dipak Kumar Raj; Jianbing Mu; Hongying Jiang; Juraj Kabat; Subash Singh; Margery Sullivan; Michael P Fay; Thomas F McCutchan; Xin-Zhuan Su
Journal:  J Biol Chem       Date:  2008-12-31       Impact factor: 5.157

5.  Structure-function aspects of PstS in multi-drug-resistant Pseudomonas aeruginosa.

Authors:  Olga Zaborina; Christopher Holbrook; Yimei Chen; Jason Long; Alexander Zaborin; Irina Morozova; Hoylan Fernandez; Yingmin Wang; Jerrold R Turner; John C Alverdy
Journal:  PLoS Pathog       Date:  2008-02-08       Impact factor: 6.823
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.