Literature DB >> 1058923

Brain damage after intrathecal methotrexate.

B Smith.   

Abstract

Ten brains from leukaemic patients given intrathecal methotrexate and 10 from leukaemic patients without intrathecal therapy have been examined. Three of the methodtrexate treated patients appear to have died from their therapy. The histological changes consisted of destruction of oligodendrocytes, sometimes complete over large areas, and sometimes relatively slight. All the patients who survived long enough after treatment showed severe astrocytosis.

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Year:  1975        PMID： 1058923      PMCID： PMC492077          DOI： 10.1136/jnnp.38.8.810

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  9 in total

1.  TRANSIENT RADIATION MYELOPATHY (WITH REFERENCE TO LHERMITTE'S SIGN OF ELECTRICAL PARAESTHESIA).

Authors:  A JONES
Journal:  Br J Radiol       Date:  1964-10       Impact factor: 3.039

2.  FOLIC ACID ANTAGONIST. EFFECTS ON THE CELL AND THE PATIENT. COMBINED CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH.

Authors:  N I BERLIN; D RALL; J A MEAD; E J FREIREICH; E VANSCOTT; R HERTZ; M B LIPSETT
Journal:  Ann Intern Med       Date:  1963-12       Impact factor: 25.391

3.  ENZYME HISTOCHEMISTRY OF THE GROWING AND ADULT OLIGODENDROCYTE.

Authors:  I Meyer; P Meyer
Journal:  Acta Neurol Scand       Date:  1964       Impact factor: 3.209

4.  Encephalopathy in acute leukaemia associated with methotrexate therapy.

Authors:  H E Kay; P J Knapton; J P O'Sullivan; D G Wells; R F Harris; E M Innes; J Stuart; F C Schwartz; E N Thompson
Journal:  Arch Dis Child       Date:  1972-06       Impact factor: 3.791

5.  Leukoencephalopathy following the administration of methotrexate into the cerebrospinal fluid in the treatment of primary brain tumors.

Authors:  H Norrell; C B Wilson; D E Slagel; D B Clark
Journal:  Cancer       Date:  1974-04       Impact factor: 6.860

6.  Necrotizing encephalopathy following intraventricular instillation of methotrexate.

Authors:  W R Shapiro; N L Chernik; J B Posner
Journal:  Arch Neurol       Date:  1973-02

7.  Brain tumor chemotherapy with intrathecal methotrexate.

Authors:  C B Wilson; H A Norrell
Journal:  Cancer       Date:  1969-05       Impact factor: 6.860

8.  Transport of methotrexate by the choroid plexus.

Authors:  R Rubin; E Owens; D Rall
Journal:  Cancer Res       Date:  1968-04       Impact factor: 12.701

9.  Somnolence after prophylactic cranial irradiation in children with acute lymphoblastic leukaemia.

Authors:  J E Freeman; P G Johnston; J M Voke
Journal:  Br Med J       Date:  1973-12-01
  9 in total
  9 in total

1.  Smaller white-matter volumes are associated with larger deficits in attention and learning among long-term survivors of acute lymphoblastic leukemia.

Authors:  Wilburn E Reddick; Zuyao Y Shan; John O Glass; Susan Helton; Xiaoping Xiong; Shengjie Wu; Melanie J Bonner; Scott C Howard; Robbin Christensen; Raja B Khan; Ching-Hon Pui; Raymond K Mulhern
Journal:  Cancer       Date:  2006-02-15       Impact factor: 6.860

2.  Prognostic factors that increase the risk for reduced white matter volumes and deficits in attention and learning for survivors of childhood cancers.

Authors:  Wilburn E Reddick; Delaram J Taghipour; John O Glass; Jason Ashford; Xiaoping Xiong; Shengjie Wu; Melanie Bonner; Raja B Khan; Heather M Conklin
Journal:  Pediatr Blood Cancer       Date:  2014-01-25       Impact factor: 3.167

3.  Necrotising leukoencephalopathy complicating treatment of childhood leukaemia.

Authors:  O Robain; O Dulac; J P Dommergues; F Bernaudin; K Diebler; C Kalifa; J Poirier
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-01       Impact factor: 10.154

4.  Voxel-based morphometry and diffusion-tensor MR imaging of the brain in long-term survivors of childhood leukemia.

Authors:  L Porto; C Preibisch; E Hattingen; M Bartels; T Lehrnbecher; R Dewitz; F Zanella; C Good; H Lanfermann; R DuMesnil; M Kieslich
Journal:  Eur Radiol       Date:  2008-05-20       Impact factor: 5.315

5.  Visual evoked potentials (VEPs) in early and late CNS changes due to antileukemia treatment in children. Preliminary report.

Authors:  E Maccolini; E Franzoni; V Vecchi; G O Bravetti; S Guidelli Guidi
Journal:  Ital J Neurol Sci       Date:  1982-12

6.  Brain lesions following combined treatment with methotrexate and craniospinal irradiation.

Authors:  F F Cruz-Sanchez; J Artigas; J Cervos-Navarro; M L Rossi; R Ferszt
Journal:  J Neurooncol       Date:  1991-04       Impact factor: 4.130

Review 7.  Quantitative morphologic evaluation of magnetic resonance imaging during and after treatment of childhood leukemia.

Authors:  Wilburn E Reddick; Fred H Laningham; John O Glass; Ching-Hon Pui
Journal:  Neuroradiology       Date:  2007-07-26       Impact factor: 2.804

Review 8.  Chemotherapy and the pediatric brain.

Authors:  Chrysanthy Ikonomidou
Journal:  Mol Cell Pediatr       Date:  2018-11-06

9.  Neuropsychological Consequences for Survivors of Childhood Brain Tumor in Malaysia.

Authors:  Hamidah Alias; Sie Chong D Lau; Ilse Schuitema; Leo M J de Sonneville
Journal:  Front Psychol       Date:  2018-05-29
  9 in total

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