Literature DB >> 10587764

Folic acid and neural tube defects. Good news at last!

G Koren1.   

Abstract

QUESTION: I read last year that Canada has followed the United States in fortifying flour with folic acid to prevent neural tube defects. Do we know yet whether this strategy is working? ANSWER: In Canada, flour is fortified with folic acid to a level of 0.15 mg/100 g. Although a mandatory date was set for November 1, 1998, most if not all companies implemented the change on or before January 1, 1998. Recent figures from the United States, where the deadline for fortification was January 1998, show that by March 1999, mean folate levels in flour doubled, substantially decreasing the risk for neural tube defects.

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Year:  1999        PMID: 10587764      PMCID: PMC2328671     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  2 in total

1.  Incidence of neural tube defects in Ontario, 1986-1999.

Authors:  Enza Gucciardi; Mary-Anne Pietrusiak; Donna L Reynolds; Jocelyn Rouleau
Journal:  CMAJ       Date:  2002-08-06       Impact factor: 8.262

2.  From genes to neural tube defects (NTDs): insights from multiscale computational modeling.

Authors:  G Wayne Brodland; Xiaoguang Chen; Paul Lee; Mungo Marsden
Journal:  HFSP J       Date:  2010-04-16
  2 in total

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