BACKGROUND: Despite advances in diagnosis, surgery, antimicrobial therapy and intensive care support, the mortality rate associated with severe secondary peritonitis remains unacceptably high. This article presents various surgical treatment strategies for severe secondary peritonitis, emphasizing the role of open management of the abdomen and planned relaparotomies. METHODS: Material was identified from previous review articles, references cited in original papers and a Medline search of the literature. RESULTS AND CONCLUSION: Surgical treatment of severe secondary peritonitis is highly demanding and very complex. The combination of improved surgical techniques, antimicrobial therapy and intensive care support has improved the outcome of such peritonitis following perforation or anastomotic disruption of the digestive tract, or infected necrotizing pancreatitis. However, aggressive surgical treatment strategies, such as open management of the abdomen and planned relaparotomies, may have reached their limits.
BACKGROUND: Despite advances in diagnosis, surgery, antimicrobial therapy and intensive care support, the mortality rate associated with severe secondary peritonitis remains unacceptably high. This article presents various surgical treatment strategies for severe secondary peritonitis, emphasizing the role of open management of the abdomen and planned relaparotomies. METHODS: Material was identified from previous review articles, references cited in original papers and a Medline search of the literature. RESULTS AND CONCLUSION: Surgical treatment of severe secondary peritonitis is highly demanding and very complex. The combination of improved surgical techniques, antimicrobial therapy and intensive care support has improved the outcome of such peritonitis following perforation or anastomotic disruption of the digestive tract, or infected necrotizing pancreatitis. However, aggressive surgical treatment strategies, such as open management of the abdomen and planned relaparotomies, may have reached their limits.
Authors: Andreas M Lenz; Mark Fairweather; James C Peyton; Sarah A Gardner; William G Cheadle Journal: Inflamm Res Date: 2010-10-26 Impact factor: 4.575
Authors: I H J T de Hingh; H van Goor; B M de Man; R M L M Lomme; R P Bleichrodt; T Hendriks Journal: Int J Colorectal Dis Date: 2005-04-05 Impact factor: 2.571
Authors: Volker Assfalg; Petra Wolf; Daniel Reim; Norbert Hüser; Georg Hellbrügge; Edouard Matevossian; Helmut Friess; Bernhard Holzmann; Klaus L Emmanuel; Alexander R Novotny Journal: Surg Today Date: 2015-07-27 Impact factor: 2.549