Literature DB >> 10583231

Tumour necrosis factor polymorphisms and susceptibility to follicular lymphoma.

J Fitzgibbon1, D Grenzelias, J Matthews, T A Lister, R K Gupta.   

Abstract

Follicular lymphoma is characterized in 85% of patients by the presence of a t(14;18) chromosomal translocation that results in overproduction of BCL2. In this study the distribution of high and low expressing TNF alleles at the TNF (-308) and LTalpha (+252) polymorphic sites in 121 patients with follicular lymphoma and 88 control individuals has been analysed. A reduction in high expressing haplotypes in patients compared to normal controls was found (P = 0.055), with no significant difference observed in response rate or overall survival between patients with high or low expressing haplotypes. These results suggest that the TNF locus, or an adjacent locus within the MHC region, is an important genetic risk factor in this disease.

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Year:  1999        PMID： 10583231     DOI： 10.1046/j.1365-2141.1999.01704.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


  10 in total

1.  Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.

Authors:  James R Cerhan; Sophia Wang; Matthew J Maurer; Stephen M Ansell; Susan M Geyer; Wendy Cozen; Lindsay M Morton; Scott Davis; Richard K Severson; Nathaniel Rothman; Charles F Lynch; Sholom Wacholder; Stephen J Chanock; Thomas M Habermann; Patricia Hartge
Journal:  Blood       Date:  2007-02-27       Impact factor: 22.113

2.  Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.

Authors:  James R Cerhan; Stephen M Ansell; Zachary S Fredericksen; Neil E Kay; Mark Liebow; Timothy G Call; Ahmet Dogan; Julie M Cunningham; Alice H Wang; Wen Liu-Mares; William R Macon; Diane Jelinek; Thomas E Witzig; Thomas M Habermann; Susan L Slager
Journal:  Blood       Date:  2007-09-07       Impact factor: 22.113

Review 3.  Host genetics in follicular lymphoma.

Authors:  James R Cerhan
Journal:  Best Pract Res Clin Haematol       Date:  2011-05-05       Impact factor: 3.020

4.  Risk Factors of Non-Hodgkin Lymphoma.

Authors:  Yawei Zhang; Ying Dai; Tongzhang Zheng; Shuangge Ma
Journal:  Expert Opin Med Diagn       Date:  2011-11-01

5.  Association of tumor necrosis factor genetic polymorphism with chronic atrophic gastritis and gastric adenocarcinoma in Chinese Han population.

Authors:  Bao-Ying Fei; Bing Xia; Chang-Sheng Deng; Xiao-Qing Xia; Min Xie; J Bart A Crusius; A Salvador Pena
Journal:  World J Gastroenterol       Date:  2004-05-01       Impact factor: 5.742

6.  IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma.

Authors:  Katherine R Calvo; Bhavana Dabir; Alexandra Kovach; Christopher Devor; Russell Bandle; Amelia Bond; Joanna H Shih; Elaine S Jaffe
Journal:  Blood       Date:  2008-08-05       Impact factor: 22.113

Review 7.  Genetic susceptibility to lymphoma.

Authors:  Christine F Skibola; John D Curry; Alexandra Nieters
Journal:  Haematologica       Date:  2007-07       Impact factor: 9.941

8.  Different role of tumor necrosis factor-α polymorphism in non-Hodgkin lymphomas among Caucasian and Asian populations: a meta-analysis.

Authors:  Kan Zhai; Jie Ding; Yan Zhou
Journal:  Int J Mol Sci       Date:  2014-05-05       Impact factor: 5.923

9.  The role of polymorphism of interleukin-2, -10, -13 and TNF-α genes in cutaneous T-cell lymphoma pathogenesis.

Authors:  Boguslaw Nedoszytko; Berenika Olszewska; Jadwiga Roszkiewicz; Jolanta Glen; Monika Zabłotna; Hanna Ługowska-Umer; Roman Nowicki; Małgorzata Sokołowska-Wojdyło
Journal:  Postepy Dermatol Alergol       Date:  2016-12-02       Impact factor: 1.837

10.  The association between the polymorphisms of TNF-α and non-Hodgkin lymphoma: a meta-analysis.

Authors:  Yong-Qiao He; Jin-Hong Zhu; Shao-Yi Huang; Zhuo Cui; Jing He; Wei-Hua Jia
Journal:  Tumour Biol       Date:  2014-09-10
  10 in total

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