| Literature DB >> 1058211 |
D Y Mason, D T Howes, C R Taylor, B D Ross.
Abstract
Purified human lysozyme (muramidase) stimulated potassium excretion by the isolated perfused rat kidney. Lysozyme is filtered and reabsorbed, without a tubular maximum. Over 90% of lysozyme filtered is retained within the kidney; 50% was recovered by enzymic assay and histologically localized to the proximal tubular cells. Hypokalaemia seen in some patients with myelomonocytic leukaemia may be directly attributed to an elevated circulating lysozyme level.Entities:
Mesh：
Substances：
Year: 1975 PMID： 1058211 PMCID： PMC475814 DOI： 10.1136/jcp.28.9.722
Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411