Literature DB >> 10581366

The multidrug resistance protein family.

P Borst1, R Evers, M Kool, J Wijnholds.   

Abstract

The human multidrug resistance protein (MRP) family contains at least six members: MRP1, the godfather of the family and well known as the multidrug resistance protein, and five homologs, called MRP2-6. In this review, we summarize what is known about the protein structure, the expression in tissues, the routing in cells, the physiological functions, the substrate specificity, and the role in multidrug resistance of the individual members of the MRP family.

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Year:  1999        PMID： 10581366     DOI： 10.1016/s0005-2736(99)00167-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  98 in total

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Review 5.  Pharmacogenomics and systems biology of membrane transporters.

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6.  Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers.

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Review 10.  Pharmacogenetics of membrane transporters: an update on current approaches.

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Journal:  Mol Biotechnol       Date:  2010-02       Impact factor: 2.695
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