Literature DB >> 10580626

A Canadian survey of prophylactic antibiotic use among hip-fracture patients.

D Zoutman1, L Chau, J Watterson, T Mackenzie, M Djurfeldt.   

Abstract

OBJECTIVE: To study how surgical prophylactic antibiotics (SPAs) were utilized in the perioperative management of surgery for hip fractures.
DESIGN: Retrospective chart review of randomly selected medical records.
SETTING: Twenty-two hospitals (teaching, nonteaching, community, and large urban referral centers) from across Canada. PATIENTS: Patients admitted in 1990 with a diagnosis of hip fracture.
METHODS: Complete medical records of 438 patients were examined; 352 cases who underwent surgical repair of a fractured hip with insertion of prosthetic material were included in analysis. Perioperative SPA use was assessed by abstracting the agent(s) chosen, dosages, time given with respect to the incision, and duration of postoperative use. Fourteen patient and process-of-care variables related to SPA were examined.
RESULTS: 247 (70%) of 352 cases did not receive a dose of SPA 2 hours preoperatively. Ten percent of preoperative SPA was administered either too early or during the procedure. In 91 (39%) of 231 cases receiving SPA, the first dose was not administered until the end of the procedure. Preoperative SPA consisted of a parenteral first-generation cephalosporin for 94% of cases. SPAs were continued more than 24 hours postoperatively in 78% of cases. Lack of a written order for SPA, being a nonteaching hospital, and shorter duration of surgical procedure were predictive of failure to receive SPA in an effective manner.
CONCLUSIONS: Most hip-fracture-surgery patients did not receive effective antibiotic prophylaxis as required to prevent serious wound infections. This important variable can be included for surveillance, so that corrective measures can be taken to assure effective prophylactic antibiotic administration.

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Mesh:

Year:  1999        PMID: 10580626     DOI: 10.1086/501577

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  6 in total

1.  Exploring obstacles to proper timing of prophylactic antibiotics for surgical site infections.

Authors:  J A Tan; V N Naik; L Lingard
Journal:  Qual Saf Health Care       Date:  2006-02

2.  Adherence to perioperative antibiotic prophylaxis among orthopedic trauma patients.

Authors:  Kristopher M Lundine; Susan Nelson; Richard Buckley; Sven Putnis; Paul J Duffy
Journal:  Can J Surg       Date:  2010-12       Impact factor: 2.089

Review 3.  Factors influencing antibiotic prophylaxis for surgical site infection prevention in general surgery: a review of the literature.

Authors:  Anna R Gagliardi; Darlene Fenech; Cagla Eskicioglu; Avery B Nathens; Robin McLeod
Journal:  Can J Surg       Date:  2009-12       Impact factor: 2.089

4.  Incidence of Nosocomial Infections in a Big University Affiliated Hospital in Shiraz, Iran: A Six-month Experience.

Authors:  Mehrdad Askarian; Hilda Mahmoudi; Ojan Assadian
Journal:  Int J Prev Med       Date:  2013-03

5.  Adherence to American society of health-system pharmacists surgical antibiotic prophylaxis guidelines in a teaching hospital.

Authors:  Mohammadreza Rafati; Afshin Shiva; Amirhosein Ahmadi; Omran Habibi
Journal:  J Res Pharm Pract       Date:  2014-04

6.  Implementing an Antimicrobial Stewardship Programme to Improve Adherence to a Perioperative Prophylaxis Guideline.

Authors:  Nehad J Ahmed; Ziyad S Almalki; Abdullah A Alfaifi; Ahmed M Alshehri; Abdullah K Alahmari; Emad Elazab; Alaa Almansour; Abdul Haseeb; Mohamed F Balaha; Amer H Khan
Journal:  Healthcare (Basel)       Date:  2022-03-01
  6 in total

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