Literature DB >> 10579607

Semi-automated entry of clinical temporal-abstraction knowledge.

Y Shahar1, H Chen, D P Stites, L V Basso, H Kaizer, D M Wilson, M A Musen.   

Abstract

OBJECTIVES: The authors discuss the usability of an automated tool that supports entry, by clinical experts, of the knowledge necessary for forming high-level concepts and patterns from raw time-oriented clinical data.
DESIGN: Based on their previous work on the RESUME system for forming high-level concepts from raw time-oriented clinical data, the authors designed a graphical knowledge acquisition (KA) tool that acquires the knowledge required by RESUME. This tool was designed using Protégé, a general framework and set of tools for the construction of knowledge-based systems. The usability of the KA tool was evaluated by three expert physicians and three knowledge engineers in three domains-the monitoring of children's growth, the care of patients with diabetes, and protocol-based care in oncology and in experimental therapy for AIDS. The study evaluated the usability of the KA tool for the entry of previously elicited knowledge. MEASUREMENTS: The authors recorded the time required to understand the methodology and the KA tool and to enter the knowledge; they examined the subjects' qualitative comments; and they compared the output abstractions with benchmark abstractions computed from the same data and a version of the same knowledge entered manually by RESUME experts.
RESULTS: Understanding RESUME required 6 to 20 hours (median, 15 to 20 hours); learning to use the KA tool required 2 to 6 hours (median, 3 to 4 hours). Entry times for physicians varied by domain-2 to 20 hours for growth monitoring (median, 3 hours), 6 and 12 hours for diabetes care, and 5 to 60 hours for protocol-based care (median, 10 hours). An increase in speed of up to 25 times (median, 3 times) was demonstrated for all participants when the KA process was repeated. On their first attempt at using the tool to enter the knowledge, the knowledge engineers recorded entry times similar to those of the expert physicians' second attempt at entering the same knowledge. In all cases RESUME, using knowledge entered by means of the KA tool, generated abstractions that were almost identical to those generated using the same knowledge entered manually.
CONCLUSION: The authors demonstrate that the KA tool is usable and effective for expert physicians and knowledge engineers to enter clinical temporal-abstraction knowledge and that the resulting knowledge bases are as valid as those produced by manual entry.

Entities:  

Mesh:

Year:  1999        PMID: 10579607      PMCID: PMC61392          DOI: 10.1136/jamia.1999.0060494

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  16 in total

Review 1.  Dimensions of knowledge sharing and reuse.

Authors:  M A Musen
Journal:  Comput Biomed Res       Date:  1992-10

2.  Knowledge-based visualization of time-oriented clinical data.

Authors:  Y Shahar; C Cheng
Journal:  Proc AMIA Symp       Date:  1998

3.  Use of data abstraction methods to simplify monitoring.

Authors:  T A Russ
Journal:  Artif Intell Med       Date:  1995-12       Impact factor: 5.326

4.  Summarization and display of on-line medical records.

Authors:  I M de Zegher-Geets; A G Freeman; M G Walker; R L Blum; G Wiederhold
Journal:  MD Comput       Date:  1988 May-Jun

5.  Ontology-based configuration of problem-solving methods and generation of knowledge-acquisition tools: application of PROTEGE-II to protocol-based decision support.

Authors:  S W Tu; H Eriksson; J H Gennari; Y Shahar; M A Musen
Journal:  Artif Intell Med       Date:  1995-06       Impact factor: 5.326

6.  Evaluation of long-term maintenance of a large medical knowledge base.

Authors:  D A Giuse; N B Giuse; R A Miller
Journal:  J Am Med Inform Assoc       Date:  1995 Sep-Oct       Impact factor: 4.497

7.  PROTEGE-II: computer support for development of intelligent systems from libraries of components.

Authors:  M A Musen; J H Gennari; H Eriksson; S W Tu; A R Puerta
Journal:  Medinfo       Date:  1995

8.  Evaluating consensus among physicians in medical knowledge base construction.

Authors:  N B Giuse; D A Giuse; R A Miller; R A Bankowitz; J E Janosky; F Davidoff; B E Hillner; G Hripcsak; M J Lincoln; B Middleton
Journal:  Methods Inf Med       Date:  1993-04       Impact factor: 2.176

9.  Knowledge-based temporal abstraction in clinical domains.

Authors:  Y Shahar; M A Musen
Journal:  Artif Intell Med       Date:  1996-07       Impact factor: 5.326

10.  Knowledge reuse: temporal-abstraction mechanisms for the assessment of children's growth.

Authors:  M M Kuilboer; Y Shahar; D M Wilson; M A Musen
Journal:  Proc Annu Symp Comput Appl Med Care       Date:  1993
View more
  6 in total

1.  Ontology acquisition from on-line knowledge sources.

Authors:  Q Li; P Shilane; N F Noy; M A Musen
Journal:  Proc AMIA Symp       Date:  2000

2.  The era of patient safety: implications for nursing informatics curricula.

Authors:  Judith A Effken; Barbara Carty
Journal:  J Am Med Inform Assoc       Date:  2002 Nov-Dec       Impact factor: 4.497

3.  Modeling fatigue.

Authors:  Walton Sumner; Jin Zhong Xu
Journal:  Proc AMIA Symp       Date:  2002

4.  Prediction in annotation based guideline encoding.

Authors:  C Greg Hagerty; David S Pickens; Jaime Chang; Casimir A Kulikowski; Frank A Sonnenberg
Journal:  AMIA Annu Symp Proc       Date:  2006

5.  Evaluation of an architecture for intelligent query and exploration of time-oriented clinical data.

Authors:  Susana B Martins; Yuval Shahar; Dina Goren-Bar; Maya Galperin; Herbert Kaizer; Lawrence V Basso; Deborah McNaughton; Mary K Goldstein
Journal:  Artif Intell Med       Date:  2008-04-28       Impact factor: 5.326

6.  Temporal query of attribute-value patient data: utilizing the constraints of clinical studies.

Authors:  Aniruddha M Deshpande; Cynthia Brandt; Prakash M Nadkarni
Journal:  Int J Med Inform       Date:  2003-04       Impact factor: 4.046

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.