Literature DB >> 10579556

Serotonin-2A receptor polymorphism (102T/C) in mood disorders

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Abstract

Serotonergic dysfunction has been implicated in mood disorders and suicidal behaviors. This study examined the association between a serotonin-2A (5HT2A) receptor gene polymorphism (102T/C) and mood disorders. The genotype and allele frequencies did not differ between patients with mood disorders and control subjects. Furthermore, the 102T/C polymorphism was not found to be associated with suicidal history in mood disorder patients. Our results suggest that this polymorphism is unlikely to play a role in the genetic susceptibility to mood disorders.

Entities:  

Year:  1999        PMID： 10579556     DOI： 10.1016/s0165-1781(99)00059-1

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  6 in total

1.  Association between HTR2A T102C polymorphism and major depressive disorder: a meta-analysis in the Chinese population.

Authors:  Chun-Xia Lin; Zhe Hu; Ze-Ming Yan; Wen Li; Yu-Sen Chen; Jiang-Hao Zhao; Liang-Qing Zhang; Bin Zhao; Wang-Tao Zhong; Du Feng
Journal:  Int J Clin Exp Med       Date:  2015-11-15

2.  Human food preferences are associated with a 5-HT(2A) serotonergic receptor polymorphism.

Authors:  P S Prado-Lima; I B M Cruz; C H A Schwanke; C A Netto; J Licinio
Journal:  Mol Psychiatry       Date:  2006-10       Impact factor: 15.992

3.  Serotonin receptors in platelets of bipolar and schizoaffective patients: effect of lithium treatment.

Authors:  Ghanshyam N Pandey; Subhash C Pandey; Xinguo Ren; Yogesh Dwivedi; Philip G Janicak
Journal:  Psychopharmacology (Berl)       Date:  2003-07-04       Impact factor: 4.530

4.  Association of the 5HTR2A gene with suicidal behavior: case-control study and updated meta-analysis.

Authors:  Thelma Beatriz González-Castro; Carlos Tovilla-Zárate; Isela Juárez-Rojop; Sherezada Pool García; Martha Patricia Velázquez-Sánchez; Alma Genis; Humberto Nicolini; Lilia López Narváez
Journal:  BMC Psychiatry       Date:  2013-01-12       Impact factor: 3.630

Review 5.  Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?

Authors:  Bruno P Guiard; Giuseppe Di Giovanni
Journal:  Front Pharmacol       Date:  2015-03-17       Impact factor: 5.810

6.  Serotonin 5-HT2A receptor activity mediates adipocyte differentiation through control of adipogenic gene expression.

Authors:  Bangning Yu; Diana M Battaglia; Timothy P Foster; Charles D Nichols
Journal:  Sci Rep       Date:  2021-10-05       Impact factor: 4.379
  6 in total

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