Multiple arterial grafts and survival.

Limitations in the long-term patency of saphenous veins for bypass grafts have encouraged interest in the use of arterial conduits. The positive effect of an internal thoracic artery graft on survival has been accepted for more than a decade, but it has proven difficult to show additional benefit from additional arterial conduits; this is probably due to multiple factors, including inappropriate choice of target vessels, short follow-up, and inadequate numbers of patients. Recently, however, the positive effect of a second arterial graft was confirmed. It will probably be difficult to show a survival benefit from a third or fourth arterial graft, but we believe that complete arterial revascularization will result in improved long-term freedom from reintervention. Interest in arterial conduits for coronary artery bypass was primarily limited to the left internal thoracic artery until the mid-1980s, when enthusiasm for the use of bilateral internal thoracic arteries grew. More recently, the gastroepiploic artery, the inferior epigastric artery, and especially the radial artery have all found advocates. However, the original conduit--and the standard against which all others are compared--is the greater saphenous vein.