BACKGROUND: To characterize postmenopausal women with endometrial polyps and to evaluate their significance. METHODS: The study population included all consecutive postmenopausal patients with a diagnosis of endometrial polyp, treated at our center over a two-year period. Demographic, medical and gynecological data were assessed with regard to the endometrial histologic findings. RESULTS: Of the 146 eligible patients, 15 had endometrial hyperplasia (four with atypia); there were no cases of endometrial carcinoma. The 20 patients (13.7%) using hormone replacement therapy had a significantly higher rate of endometrial hyperplasia than non-hormone users (p<0.006). No differences were observed among the endometrial histological categories for any of the presenting symptoms and signs, ultrasonographic findings, or medical histories. CONCLUSIONS: Postmenopausal endometrial polyp is a common, mostly benign entity. However, the relatively high rate of concomitant endometrial hyperplasia, especially in patients receiving hormone replacement therapy, dictates a thorough histological evaluation in all cases.
BACKGROUND: To characterize postmenopausal women with endometrial polyps and to evaluate their significance. METHODS: The study population included all consecutive postmenopausal patients with a diagnosis of endometrial polyp, treated at our center over a two-year period. Demographic, medical and gynecological data were assessed with regard to the endometrial histologic findings. RESULTS: Of the 146 eligible patients, 15 had endometrial hyperplasia (four with atypia); there were no cases of endometrial carcinoma. The 20 patients (13.7%) using hormone replacement therapy had a significantly higher rate of endometrial hyperplasia than non-hormone users (p<0.006). No differences were observed among the endometrial histological categories for any of the presenting symptoms and signs, ultrasonographic findings, or medical histories. CONCLUSIONS: Postmenopausal endometrial polyp is a common, mostly benign entity. However, the relatively high rate of concomitant endometrial hyperplasia, especially in patients receiving hormone replacement therapy, dictates a thorough histological evaluation in all cases.
Authors: Navya Nair; Olga Camacho-Vanegas; Dmitry Rykunov; Matthew Dashkoff; Sandra Catalina Camacho; Cassie A Schumacher; Jonathan C Irish; Timothy T Harkins; Elijah Freeman; Isaac Garcia; Elena Pereira; Sviatoslav Kendall; Rachel Belfer; Tamara Kalir; Robert Sebra; Boris Reva; Peter Dottino; John A Martignetti Journal: PLoS Med Date: 2016-12-27 Impact factor: 11.069
Authors: Marco Antonio Lenci; Vanessa Alessandra Lui do Nascimento; Ana Beatriz Grandini; Walid Makin Fahmy; Daniella de Batista Depes; Fausto Farah Baracat; Reginaldo Guedes Coelho Lopes Journal: Einstein (Sao Paulo) Date: 2014 Jan-Mar