Literature DB >> 10576697

Further hypotensive metabolites from Verbesina caracasana.

G Delle Monache1, A R Volpe, F Delle Monache, A Vitali, B Botta, R Espinal, S C De Bonnevaux, C De Luca, M Botta, F Corelli, M Carmignani.   

Abstract

After the isolation of caracasanamide and caracasandiamide, further hypotensive components of Verbesina caracasana were shown to be N3-prenylagmatine, N1-3',4'-dimethoxycinnamoylagmatine, agmatine and galegin (prenylguanidine). The structures were assigned on the basis of the spectral data of both metabolites and products from their alkaline hydrolyses. A pharmacological analysis of these products is also presented.

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Year:  1999        PMID: 10576697     DOI: 10.1016/s0960-894x(99)00569-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

Review 1.  Bioactive cyclobutane-containing alkaloids.

Authors:  Valery M Dembitsky
Journal:  J Nat Med       Date:  2007-09-05       Impact factor: 2.343

  1 in total

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