M Reljic1, V Vlaisavljević. 1. Department of Gynecology and Perinatology, Maribor Teaching Hospital, Maribor, Slovenia.
Abstract
PURPOSE: The aim of the study was to find whether inferences to the possible success of natural IVF/ICSI cycles could be drawn from the estradiol (E2) pattern. METHODS: Sixty-eight women who underwent oocyte recovery in 98 natural cycles were recruited for the study. Daily serum E2 was measured in the preovulatory phase (-3 to +2 day). The E2 pattern was compared among four groups: Group A, unsuccessful egg retrieval; Group B, no fertilization; Group C, no implantation; and Group D, implantation. RESULTS: There was no difference in mean E2 levels between groups. Only the ratio of E2 on day +1/E2 on day 0 was significantly lower in conception cycles in comparison with nonconception cycles. In cycles with a decreased E2 level on day +1, only the implantation rate was significantly higher in comparison with cycles with an increasing E2 level. CONCLUSIONS: From the E2 pattern it is possible to make inferences about the likelihood of implantation but not the fertilization or oocyte recovery success.
PURPOSE: The aim of the study was to find whether inferences to the possible success of natural IVF/ICSI cycles could be drawn from the estradiol (E2) pattern. METHODS: Sixty-eight women who underwent oocyte recovery in 98 natural cycles were recruited for the study. Daily serum E2 was measured in the preovulatory phase (-3 to +2 day). The E2 pattern was compared among four groups: Group A, unsuccessful egg retrieval; Group B, no fertilization; Group C, no implantation; and Group D, implantation. RESULTS: There was no difference in mean E2 levels between groups. Only the ratio of E2 on day +1/E2 on day 0 was significantly lower in conception cycles in comparison with nonconception cycles. In cycles with a decreased E2 level on day +1, only the implantation rate was significantly higher in comparison with cycles with an increasing E2 level. CONCLUSIONS: From the E2 pattern it is possible to make inferences about the likelihood of implantation but not the fertilization or oocyte recovery success.
Authors: Anja Helmer; Isotta Magaton; Odile Stalder; Petra Stute; Daniel Surbek; Michael von Wolff Journal: Front Endocrinol (Lausanne) Date: 2022-05-26 Impact factor: 6.055