Literature DB >> 10575372

Aggregation inhibitory activity of minor acetophenones from Paeonia species.

H C Lin1, H Y Ding, F N Ko, C M Teng, Y C Wu.   

Abstract

Two minor acetophenones, 2,5-dihydroxy-4-methoxy-acetophenone (2) and 2,5-dihydroxy-4-methylacetophenone (7) from Paeonia species were found to selectively inhibit the aggregation of rabbit platelets induced by arachidonic acid. They were more potent than the major compound, paeonol (1), and 7 also inhibited the formation of TXA2 and PGD2 from arachidonic acid.

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Year:  1999        PMID： 10575372     DOI： 10.1055/s-1999-14030

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  11 in total

1.  Action potential bursts in central snail neurons elicited by paeonol: roles of ionic currents.

Authors:  Yi-hung CHEN; Pei-lin LIN; Hui-yu HSU; Ya-ting WU; Han-yin YANG; Dah-yuu LU; Shiang-suo HUANG; Ching-liang HSIEH; Jaung-geng LIN
Journal:  Acta Pharmacol Sin       Date:  2010-11-01       Impact factor: 6.150

2.  Anti-inflammatory and Anti-oxidative Activities of Paeonol and Its Metabolites Through Blocking MAPK/ERK/p38 Signaling Pathway.

Authors:  Xin Jin; Jing Wang; Zi-Ming Xia; Chang-Hui Shang; Qiu-Li Chao; Ya-Ru Liu; Hua-Ying Fan; Da-Quan Chen; Feng Qiu; Feng Zhao
Journal:  Inflammation       Date:  2016-02       Impact factor: 4.092

3.  Paeonol Interferes With Quorum-Sensing in Pseudomonas aeruginosa and Modulates Inflammatory Responses In Vitro and In Vivo.

Authors:  Huaqiao Tang; Dan Yang; Ling Zhu; Fei Shi; Gang Ye; Hongrui Guo; Huidan Deng; Ling Zhao; Zhiwen Xu; Yinglun Li
Journal:  Front Immunol       Date:  2022-05-24       Impact factor: 8.786

4.  Anti-inflammatory and anticoagulative effects of paeonol on LPS-induced acute lung injury in rats.

Authors:  Pin-Kuei Fu; Chieh-Liang Wu; Tung-Hu Tsai; Ching-Liang Hsieh
Journal:  Evid Based Complement Alternat Med       Date:  2012-02-21       Impact factor: 2.629

5.  Two new chroman derivations from the endophytic Penicillium sp. DCS523.

Authors:  Jun-Tian Li; Xiao-Li Fu; Chun Tan; Ying Zeng; Qi Wang; Pei-Ji Zhao
Journal:  Molecules       Date:  2011-01-18       Impact factor: 4.411

Review 6.  A Review of Antiplatelet Activity of Traditional Medicinal Herbs on Integrative Medicine Studies.

Authors:  Kyungho Kim; Kwang-Il Park
Journal:  Evid Based Complement Alternat Med       Date:  2019-01-03       Impact factor: 2.629

7.  Root Bark of Paeonia suffruticosa Extract and Its Component Methyl Gallate Possess Peroxynitrite Scavenging Activity and Anti-inflammatory Properties through NF-κB Inhibition in LPS-treated Mice.

Authors:  Dong Jin Park; Hee Jin Jung; Chan Hum Park; Takako Yokozawa; Ji-Cheon Jeong
Journal:  Molecules       Date:  2019-09-25       Impact factor: 4.411

8.  Dietary Moutan Cortex Radicis Improves Serum Antioxidant Capacity and Intestinal Immunity and Alters Colonic Microbiota in Weaned Piglets.

Authors:  Miaomiao Bai; Hongnan Liu; Shanshan Wang; Qingyan Shu; Kang Xu; Jian Zhou; Xia Xiong; Ruilin Huang; Jinping Deng; Yulong Yin; Zheng'an Liu
Journal:  Front Nutr       Date:  2021-06-17

9.  Simultaneous determination of ten bioactive compaounds from the roots of Cynanchum paniculatum by using high performance liquid chromatography coupled-diode array detector.

Authors:  Jin Bae Weon; Bohyoung Lee; Bo-Ra Yun; Jiwoo Lee; Choong Je Ma
Journal:  Pharmacogn Mag       Date:  2012-07       Impact factor: 1.085

10.  Cortex Moutan Induces Bladder Cancer Cell Death via Apoptosis and Retards Tumor Growth in Mouse Bladders.

Authors:  Mei-Yi Lin; Ying-Ray Lee; Su-Yin Chiang; Yi-Zhen Li; Yueh-Sheng Chen; Cheng-Da Hsu; Yi-Wen Liu
Journal:  Evid Based Complement Alternat Med       Date:  2013-10-24       Impact factor: 2.629
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