| Literature DB >> 10574749 |
Abstract
Natural killer cells attack tumor cells, infected cells and some normal cells, but the basis of their specificity is not completely understood. Recent studies indicate that epithelial tumor cells upregulate a stress-induced MHC class-I-like protein termed MICA, triggering NK cells via a recently described receptor called NKG2D.Entities:
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Year: 1999 PMID： 10574749 DOI： 10.1016/s0960-9822(00)80044-5
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834