Ultrasound during pregnancy and birthweight, childhood malignancies and neurological development.

The present paper summarizes some of the epidemiological studies of in utero ultrasound exposure and subsequent childhood development. Emphasis is placed on birthweight, childhood malignancies and neurological development. A meta-analysis, including neurological outcomes such as handedness, speech development, motor development, hearing and vision, is presented. The epidemiological evidence does not indicate any association between diagnostic ultrasound exposure during pregnancy and reduced birthweight, childhood malignancies or neurological maldevelopment. The possible association between ultrasound and nonrighthandedness among boys needs further evaluation.