Literature DB >> 10574

Multiple factor analysis of the action of local anesthetics.

H C Lin, I Ueda, H Eyring.   

Abstract

The pH jump data of Bianchi and Strobel [(1968) Trans. N.Y. Acad. Sci. Ser. II, 30, 1082-1092] on desheathed frog sciatic nerve are fitted to rate equations. A general quantitation of synergism, summation, and antagonism of anesthetics and of excitation is given.

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Year:  1976        PMID： 10574      PMCID： PMC431192          DOI： 10.1073/pnas.73.10.3726

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  6 in total

1.  Molecular mechanism of inhibition of firefly luminescence by local anesthetics.

Authors:  I Ueda; H Kamaya; H Eyring
Journal:  Proc Natl Acad Sci U S A       Date:  1976-02       Impact factor: 11.205

2.  [Protein binding of local anesthetics].

Authors:  K Nishimura; R Hamai; E Kitamura; M Fujimori
Journal:  Masui       Date:  1975-03

3.  Local anesthetics. I. The blocking potencies of some local anesthetics and of butyl alcohol determined on peripheral nerves.

Authors:  J C SKOU
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1954

4.  On the active structure of local anesthetics.

Authors:  J M RITCHIE; P GREENGARD
Journal:  J Pharmacol Exp Ther       Date:  1961-08       Impact factor: 4.030

5.  The site of action and active form of local anesthetics. I. Theory and pH experiments with tertiary compounds.

Authors:  T Narahashi; T Frazier; M Yamada
Journal:  J Pharmacol Exp Ther       Date:  1970-01       Impact factor: 4.030

6.  Modes of action of local anesthetics in nerve and muscle in relation to their uptake and distribution.

Authors:  C P Blanchi; G E Strobel
Journal:  Trans N Y Acad Sci       Date:  1968-06
  6 in total

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